Dr. Darren McGuire, MD

• Cardiology

• Internal Medicine

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• Duke University Medical Center

  Residency Hospital

• Vet Admin Medical Center

  Residency Hospital

• Duke University Hospital

  Fellowship Hospital, 2001

• University Of Texas Southwestern Medical Center

  Fellowship Hospital, 1997

• University Of Texas Southwestern Medical Center

  Internship Hospital, 1994

• The Dallas Bed Rest and Training Study: Revisited after 50 years, 2019-10-14

• Rationale, design, and baseline characteristics of the CArdiovascular safety and Renal Microvascular outcomE study with LINAgliptin (CARMELINA®): a randomized, double-blind, placebo-controlled clinical trial in patients with type 2 diabetes and high cardio-renal risk, 2018-03-14

• Lower rates of cardiovascular events and mortality associated with liraglutide use in patients treated with basal insulin - A DEVOTE subanalysis (DEVOTE 10), 2019-04-01

• Relation of Regional Fat Distribution to Left Ventricular Structure and Function Neeland et al: Fat Distribution and Cardiac Morphology, 2013-08-08

• No Association between Hemoglobin A1c and In-Hospital Mortality in Patients with Diabetes and Acute Myocardial Infarction, 2011-10-11

• Differential Associations between Soluble Cellular Adhesion Molecules and Atherosclerosis in the Dallas Heart Study: a Distinct Role for Soluble Endothelial Cell-Selective Adhesion Molecule, 2009-08-27

• Development and validation of a model to predict cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke in patients with type 2 diabetes mellitus and established atherosclerotic cardiovascular disease, 2022-08-27

• Transitioning to active-controlled trials to evaluate cardiovascular safety and efficacy of medications for type 2 diabetes, 2022-08-24

• Age and Sex Dependent Upper Reference Limits for the High Sensitivity Cardiac Troponin T Assay, 2014-02-12

• Patterns and Predictors of Intensive Statin Therapy among Patients with Diabetes Mellitus after Acute Myocardial Infarction, 2014-01-31

• Physical Activity Participation, Health Perceptions, and CVD Mortality in a Multi-Ethnic Population: The Dallas Heart Study, 2012-11-28

• A Safety Evaluation of Empagliflozin for the Treatment of Type 2 Diabetes, 2016-02-02

• Heart Failure Endpoints in Cardiovascular Outcome Trials of SGLT2 inhibitors in Patients with Type 2 Diabetes: A Critical Evaluation of Clinical and Regulatory Issues, 2019-12-16

• Does the "July effect” of new trainees at teaching hospitals impact outcomes for patients hospitalized with heart failure? Real-world analyses of more than half a million US admissions, 2021-11-27

• Development and validation of optimal phenomapping methods to estimate long-term atherosclerotic cardiovascular disease risk in patients with type 2 diabetes, 2021-03-13

• Sex-Based Differences in Cardiometabolic Biomarkers, 2017-02-07

• Association of Intensive Lifestyle Intervention, Fitness and Body Mass Index with Risk of Heart Failure in Overweight or Obese Adults with Type 2 Diabetes Mellitus: An Analysis from the Look AHEAD trial, 2020-03-05

• Prevalent and Incident Heart Failure in Cardiovascular Outcome Trials of Patients with Type 2 Diabetes, 2018-03-10

• Recognition of Incident Diabetes Mellitus during an Acute Myocardial Infarction, 2015-04-21

• Mediators of ertugliflozin effects on heart failure and kidney outcomes among patients with type 2 diabetes, 2022-06-15

• Efficacy and safety of sodium-glucose cotransporter 2 inhibitors initiation in patients with acute heart failure, with and without type 2 diabetes: a systematic review and meta-analysis, 2022-02-05

• Differences in glycemic control between the treatment arms in cardiovascular outcome trials of type 2 diabetes medications do not explain cardiovascular benefits, 2021-04-15

• Association of prediabetes by fasting glucose and/or haemoglobin A1c levels with subclinical atherosclerosis and impaired renal function: Observations from the Dallas Heart Study, 2017-12-07

• Target Organ Complications and Cardiovascular Events Associated with Masked Hypertension and White Coat Hypertension: Analysis from the Dallas Heart Study, 2015-11-17

• Ertugliflozin, renoprotection and potential confounding by muscle wasting. Reply to Groothof D, Post A, Gans ROB et al [letter], 2022-03-03

• Comparison of Accuracy of Estimation of Cardiac Output by Thermodilution Versus the Fick Method Using Measured Oxygen Uptake, 2022-05-22

• Interactions Between Smoking, Pulmonary Surfactant Protein B, and Atherosclerosis in the General Population: The Dallas Heart Study, 2011-08-04

• Longitudinal Changes in Serum 25-Hydroxyvitamin D in the Dallas Heart Study, 2017-06-14

• Cardiac arrhythmias and conduction abnormalities in patients with type 2 diabetes, 2023-01-21

• Ertugliflozin and incident obstructive sleep apnea: an analysis from the VERTIS CV trial, 2022-05-20

• Sodium-glucose co-transporter inhibition in the treatment of diabetes: Sweetening the pot, 2015-03-09

• A Multimodality Strategy for Cardiovascular Risk Assessment: Performance in Two Population-Based Cohorts, 2017-03-30

• Atovaquone for treatment of COVID-19: A prospective randomized, double-blind, placebo-controlled clinical trial 10.3389/fphar.2022.1020123, 2022-09-30

• Empagliflozin Reduced Mortality and Hospitalization for Heart Failure Across the Spectrum of Cardiovascular Risk in the EMPA-REG OUTCOME Trial, 2018-12-06

• The Association Between HDL Particle Concentration and Incident Metabolic Syndrome in the Multi-ethnic Dallas Heart Study, 2016-12-12

• The Reliability and Prognosis of In-Hospital Diagnosis of Metabolic Syndrome in the Setting of Acute Myocardial Infarction, 2013-04-03

• State-of-the-Art: Hypo-responsiveness to oral antiplatelet therapy in patients with type 2 diabetes mellitus, 2015-01-29

• Residual Angina Following Elective Percutaneous Coronary Intervention in Patients with Diabetes, 2017-09-07

• Bleeding Risk Following Percutaneous Coronary Intervention in Patients with Diabetes Prescribed Dual Anti-platelet Therapy, 2016-10-02

• Association between Diabetes Mellitus and Angina After Acute Myocardial Infarction. Analysis of the TRIUMPH Prospective Cohort Study, 2014-04-16

• Kidney outcomes using a sustained =40% decline in eGFR : A meta-analysis of SGLT2 inhibitor trials, 2021-06-15

• Associations of visceral and abdominal subcutaneous adipose tissue with markers of cardiac and metabolic risk in obese adults, 2013-05-19

• Association of Growth Differentiation Factor-15 with Coronary Atherosclerosis and Mortality in a Young, Multiethnic Population: Observations from the Dallas Heart Study, 2011-11-07

• Disparities in Counseling for Lifestyle Modification Among Obese Adults: Insights from the Dallas Heart Study, 2011-08-04

• Patterns of Prescribing Sodium-Glucose Cotransporter-2 Inhibitors for Medicare Beneficiaries in the United States, 2021-11-15

• Relation of plasma ceramides to visceral adiposity, insulin resistance and the development of type 2 diabetes mellitus: the Dallas Heart Study, 2018-08-29

• Mitochondrial metabolites predict adverse cardiovascular events in individuals with diabetes, 2023-09-08

• Secondary Prevention of Cardiovascular Disease in Patients with Type 2 Diabetes: International Insights from the TECOS Trial, 2017-06-16

• Assessing use of patient-focused pharmacotherapy in glycemic management through the Diabetes Collaborative Registry (DCR), 2018-08-09

• Prevalence of Glucose Abnormalities Among Patients Presenting with an Acute Myocardial Infarction, 2014-07-11

• Electrocardiographic patterns of proximal left anterior descending artery occlusion in ST-elevation myocardial infarction may be modified by three-vessel coronary artery disease, 2012-01-14

• Sitagliptin does not reduce the risk of cardiovascular death or hospitalization for heart failure following myocardial infarction in patients with diabetes: observations from TECOS, 2019-09-03

• Insulin Resistance is Associated with Significant Clinical Atherosclerosis in Non-Diabetic Patients with Acute Myocardial Infarction, 2013-07-18

• 2022 Beijing Winter Olympics -Spotlight on Cardiac Metabolism, 2022-05-23

• Hypertension Control in Adults With Diabetes and Recurrent Cardiovascular Events: Global Results From the TECOS Trial, 2017-08-28

• Predicting adverse outcomes after myocardial infarction among patients with diabetes mellitus, 2016-05-24

• In-hospital Initiation of Sodium Glucose Cotransporter-2 Inhibitors for Heart Failure with Reduced Ejection Fraction, 2021-11-16

• Use of Glucagon-Like Peptide-1 Receptor Agonists in Patients With Type 2 Diabetes and Cardiovascular Disease A Review, 2020-10-01

• Metabolomic Profiling of the Effects of Dapagliflozin in Heart Failure with Reduced Ejection Fraction: DEFINE-HF, 2022-05-23

• Type of Beta-blocker Use Among Patients with Versus without Diabetes after Myocardial Infarction, 2014-06-09

• Impact of Empagliflozin in Patients with Diabetes and Heart Failure, 2016-08-04

• Relation of Black Race between High Density Lipoprotein Cholesterol Content, High Density Lipoprotein Particles and Coronary Events (From the Dallas Heart Study), 2015-01-15

• Higher Natriuretic Peptide Levels Associate with a Favorable Adipose Tissue Distribution Profile, 2013-04-16

• Heart Failure Risk Stratification and Efficacy of Sodium-Glucose Cotransporter-2 Inhibitors in Patients with Type 2 Diabetes Mellitus, 2019-08-31

• Lactic acidosis incidence with metformin in patients with type 2 diabetes and chronic kidney disease: A retrospective nested case-control study, 2020-07-17

• DEVOTE 3: temporal relationships between severe hypoglycaemia, cardiovascular outcomes and mortality, 2017-09-15

• Tirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis, 2022-02-24

• Biomarkers of Chronic Cardiac Injury and Hemodynamic Stress Identify a Malignant Phenotype of Left Ventricular Hypertrophy in the General Population, 2012-12-05

• Race-Specific Associations of Myeloperoxidase with Atherosclerosis in a Population-Based Sample: The Dallas Heart Study, 2011-08-22

• Circulating levels of matrix metalloproteinase-9 and abdominal aortic pathology: From the Dallas Heart Study, 2012-12-12

• Effects of ertugliflozin on kidney composite outcomes, renal function and albuminuria in patients with type 2 diabetes mellitus: an analysis from the randomised VERTIS CV trial, 2021-03-04