Dr. William Kraus, MD

• Cardiology

• Internal Medicine

*Healthgrades does not verify qualifications for medical specialties. Please verify your provider's specialty and qualifications directly with your provider and applicable medical board.

• Duke University

  Medical School, 1982

• PDPR Gene Expression Correlates with Exercise-Training Insulin Sensitivity Changes, 2016-07-20

• Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid arthritis: a pilot study, 2018-06-14

• Sex-dimorphic gene effects on survival outcomes in people with coronary artery disease, 2022-06-14

• Associations Between Residential Proximity to Traffic and Vascular Disease in a Cardiac Catheterization Cohort, 2017-11-30

• Confirmation of Statin and Fibrate Use from Small-Volume Archived Plasma Samples by High-Throughput LC-MS/MS Method, 2023-04-27

• Systematic review of the prospective association of daily step counts with risk of mortality, cardiovascular disease, and dysglycemia, 2020-06-20

• Short-term effects of fine particulate matter and ozone on the cardiac conduction system in patients undergoing cardiac catheterization, 2018-10-11

• Genetic inactivation ofANGPTL4improves glucose homeostasis and is associated with reduced risk of diabetes, 2018-06-13

• A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN Experience, 2015-08-14

• A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease, 2018-07-09

• Metabolomic profiling identifies complex lipid species and amino acid analogues associated with response to weight loss interventions, 2021-05-27

• Daily Energy Expenditure through the Human Life Course, 2021-08-13

• Accelerated epigenetic age as a biomarker of cardiovascular sensitivity to traffic-related air pollution, 2020-12-07

• A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease, 2022-01-17

• Genetic Variation in Acid Ceramidase Predicts Non-completion of an Exercise Intervention, 2018-06-29

• A whole blood gene expression-based signature for smoking status, 2012-12-03

• Impact on Cardiometabolic Risk of a Weight Loss Intervention with Higher Protein from Lean Red Meat: Combined Results of Two Randomized Controlled Trials in Obese Middle-aged and Older Adults, 2019-10-02

• Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts, 2022-07-11

• Using Machine Learning to Identify Organ System Specific Limitations to Exercise Via Cardiopulmonary Exercise Testing, 2022-08-11

• High-Intensity Interval Training for Cardiometabolic Disease Prevention, 2019-02-27

• Protein biomarkers of cardiac remodeling and inflammation associated with HFpEF and incident events, 2022-11-22

• Effect of high-intensity interval training on muscle remodeling in rheumatoid arthritis compared to prediabetes, 2018-12-27

• Effects of Two Years of Calorie Restriction on Aerobic Capacity and Muscle Strength, 2017-06-28

• Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients, 2011-03-28

• Transcriptomics for Clinical and Experimental Biology Research: Hang on a Seq, 2023-01-17

• Effect of two years of calorie restriction on liver biomarkers: Results from the CALERIE phase 2 randomized controlled trial., 2020-08-14

• Combined Inflammation and Metabolism Biomarker Indices of Robust and Impaired Physical Function in Older Adults, 2018-05-08

• A Putatively Functional Polymorphism in theHTR2CGene is Associated with Depressive Symptoms in White Females Reporting Significant Life Stress, 2014-12-16

• Metabolic Dysfunction in Heart Failure: Diagnostic, Prognostic, and Pathophysiologic Insights From Metabolomic Profiling, 2017-05-03

• A standard calculation methodology for human doubly labeled water studies, 2021-02-16

• Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass, 2017-11-07

• Genome-Wide Linkage Analysis of Cardiovascular Disease Biomarkers in a Large, Multigenerational Family, 2013-08-02

• Aspirin Exposure Reveals Novel Genes Associated with Platelet Function and Cardiovascular Events, 2013-07-03

• Trends in Cardiorespiratory Fitness: The Evolution of Exercise Treadmill Testing at a Single Academic Medical Center from 1970 to 2012, 2019-01-16

• Atherogenic Lipoprotein Determinants of Cardiovascular Disease and Residual Risk Among Individuals With Low Low-Density Lipoprotein Cholesterol, 2017-07-21

• Effects of Exercise Training on Health Status in Patients With Chronic Heart Failure: Findings From the HF-ACTION Randomized Controlled Trial, 2009-04-08

• Large meta-analysis of genome-wide association studies identifies five loci for lean body mass, 2017-07-19

• Thyroid Hormone Status Regulates Skeletal Muscle Response to Chronic Motor Nerve Stimulation, 2019-10-31

• Developing a synthetic psychosocial stress measure and harmonizing CVD-risk data: a way forward to GxE meta- and mega-analyses, 2018-07-24

• Human and Mouse Skeletal Muscle Stem Cells: Convergent and Divergent Mechanisms of Myogenesis, 2014-02-28

• Relationship of -Blocker Dose with Outcomes in Ambulatory Heart Failure Patients with Systolic Dysfunction: Results from the HF-ACTION Trial, 2012-05-02

• Genome-Wide Variants Associated With Longitudinal Survival Outcomes Among Individuals With Coronary Artery Disease, 2021-06-01

• Longevity-related molecular pathways are subject to midlife "switch” in humans, 2019-06-06

• Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis, 2015-11-05

• Modest Increase in Peak VO2is Related to Better Clinical Outcomes in Chronic Heart Failure Patients: Results from Heart Failure and a Controlled Trial to Investigate Outcomes of Exercise Training (HF-ACTION), 2012-07-06

• Variation in human water turnover associated with environmental and lifestyle factors, 2022-11-24

• Polygenic Score for Beta-Blocker Survival Benefit in European Ancestry Patients with Reduced Ejection Fraction Heart Failure, 2020-10-04

• Effects of aerobic training with and without weight loss on insulin sensitivity and lipids, 2018-05-18

• Greater male variability in daily energy expenditure develops through puberty, 2023-09-20

• SLCO1B1genetic variants, long-term low-density lipoprotein cholesterol levels and clinical events in patients following cardiac catheterization, 2016-01-01

• Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci, 2021-04-30

• Exercise Biology and Medicine: Innovative Research to Improve Global Health, 2014-03-25

• Effects of exercise training alone vs a combined exercise and nutritional lifestyle intervention on glucose homeostasis in prediabetic individuals: a randomised controlled trial, 2016-07-15

• Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients, 2017-11-21

• Impact of Age on Comorbidities and Outcomes in Heart Failure with Reduced Ejection Fraction, 2019-12-06

• Association between Bout Duration of Physical Activity and Health: Systematic Review, 2019-02-27

• Rejuvenation of Neutrophil Functions in Association With Reduced Diabetes Risk Following Ten Weeks of Low-Volume High Intensity Interval Walking in Older Adults With Prediabetes - A Pilot Study, 2020-05-05

• Utility of Growth Differentiation Factor-15, a Marker of Oxidative Stress and Inflammation, in Chronic Heart Failure: Insights From the HF-ACTION Study, 2021-03-22

• Response, 2014-11-07

• The Relation of Accelerometer-Measured Physical Activity and Serum Uric Acid Using the National Health and Nutrition Survey (NHANES) 2003-2004, 2022-01-12

• Evaluating Individual Level Responses to Exercise for Health Outcomes in Overweight or Obese Adults, 2019-11-14

• Response, 2020-02-06

• Variables Measured during Cardiopulmonary Exercise Testing as Predictors of Mortality in Chronic Systolic Heart Failure, 2016-02-23

• Differential Effects of Amount, Intensity, and Mode of Exercise Training on Insulin Sensitivity and Glucose Homeostasis: A Narrative Review, 2022-07-14

• Relationship of physical function to vastus lateralis capillary density and metabolic enzyme activity in elderly men and women, 2013-04-02

• The association of accelerated epigenetic age with all-cause mortality in cardiac catheterization patients as mediated by vascular and cardiometabolic outcomes, 2022-12-03

• EXERCISE AMONG BREAST AND PROSTATE CANCER SURVIVORS - WHAT ARE THEIR BARRIERS?, 2011-05-20

• Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm, 2020-05-05

• Total daily energy expenditure has declined over the last 3 decades due to declining basal expenditure not reduced activity expenditure., 2023-04-26

• Novel plasma biomarkers improve discrimination of metabolic health independent of weight, 2020-12-07

• A genome-wide trans-ethnic interaction study links thePIGR-FCAMRlocus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic, 2017-03-29

• Use of the Corus® CAD Gene Expression Test for Assessment of Obstructive Coronary Artery Disease Likelihood in Symptomatic Non-Diabetic Patients, 2013-08-26

• Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition, 2022-01-10

• Effects of 2 years of caloric restriction on oxidative status assessed by urinary F2-isoprostanes: The CALERIE 2 randomized clinical trial, 2018-02-09

• TheACTN3R577X Polymorphism Is Associated with Cardiometabolic Fitness in Healthy Young Adults, 2015-06-24

• Making Cardiopulmonary Exercise Testing Interpretable for Clinicians, 2021-10-01

• Challenges in defining successful adherence to calorie restriction goals in humans: Results from CALERIE™ 2, 2022-02-28

• ANGPTL3 Deficiency and Protection Against Coronary Artery Disease, 2017-04-03

• Evaluating DNA methylation age on the Illumina MethylationEPIC Bead Chip, 2019-04-19

• Tryptophan Metabolism and Neurodegeneration: Longitudinal Associations of Kynurenine Pathway Metabolites with Cognitive Performance and Plasma ADRD Biomarkers in the Duke Physical Performance Across the LifeSpan Study, 2023-03-25

• Response, 2013-12-31

• Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease, 2017-02-21

• Daily Step Counts for Measuring Physical Activity Exposure and Its Relation to Health, 2019-02-22

• Fine mapping of a linkage peak with integration of lipid traits identifies novel coronary artery disease genes on chromosome 5, 2012-02-27

• A Practical and Time-Efficient High-Intensity Interval Training Program Modifies Cardio-Metabolic Risk Factors in Adults with Risk Factors for Type II Diabetes, 2017-09-08

• Altered skeletal muscle metabolic pathways, age, systemic inflammation, and low cardiorespiratory fitness associate with improvements in disease activity following high-intensity interval training in persons with rheumatoid arthritis, 2021-07-10

• Energy compensation and adiposity in humans, 2021-08-27

• Race, exercise training, and outcomes in chronic heart failure: Findings from Heart Failure - A Controlled Trial Investigating Outcomes in Exercise TraiNing (HF-ACTION), 2013-07-12

• Physical Activity, All-Cause and Cardiovascular Mortality, and Cardiovascular Disease, 2019-02-22

• Rationale and design of "Hearts & Parks”: study protocol for a pragmatic randomized clinical trial of an integrated clinic-community intervention to treat pediatric obesity, 2020-06-26

• The genetic basis for survivorship in coronary artery disease, 2013-09-27

• Gene Expression Patterns in Peripheral Blood Correlate with the Extent of Coronary Artery Disease, 2009-09-14

• The effects of increasing exercise intensity and dose on multiple measures of high-density lipoprotein function, 2018-02-08

• Corrigendum: Genome-Wide Variants Associated With Longitudinal Survival Outcomes Among Individuals With Coronary Artery Disease, 2021-07-27

• Associations between neighborhood socioeconomic cluster and hypertension, diabetes, myocardial infarction, and coronary artery disease within a cohort of cardiac catheterization patients, 2021-10-02

• Effects of Amount, Intensity, and Mode of Exercise Training on Insulin Resistance and Type 2 Diabetes Risk in the STRRIDE Randomized Trials, 2021-02-04

• Variability in energy expenditure is much greater in males than females, 2022-09-15

• The effects of exercise on the lipoprotein subclass profile: a meta-analysis of 10 interventions, 2015-10-17

• A Role for Exercise to Counter Skeletal Muscle Clock Disruption, 2020-12-26

• Impact of Baseline Physical Activity and Diet Behavior on Metabolic Syndrome in a Pharmaceutical Trial: Results from NAVIGATOR, 2014-01-15

• Physiology of Sedentary Behavior and Its Relationship to Health Outcomes, 2014-09-25