Dr. Steven Frank, MD

• Radiation Oncology

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• Emory University School Of Medicine

  Medical School, 2000

• Design and fabrication of a 3D-printed oral stent for head and neck radiotherapy from routine diagnostic imaging, 2017-11-16

• Multidisciplinary Management of Lacrimal Sac/Nasolacrimal Duct Carcinomas, 2013-09-21

• Health Care Resource Utilization for Esophageal Cancer Using Proton versus Photon Radiation Therapy, 2022-06-23

• Imaging and clinical data archive for head and neck squamous cell carcinoma patients treated with radiotherapy, 2018-09-04

• MRI-guided brachytherapy, 2014-07-16

• Proton Therapy for HPV-Associated Oropharyngeal Cancers of the Head and Neck: a De-Intensification Strategy, 2021-06-04

• Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance, 2021-06-29

• Correction to: Long-term patient reported outcomes following radiation therapy for oropharyngeal cancer: cross-sectional assessment of a prospective symptom survey in patients =65 years old, 2017-11-23

• Prospective Longitudinal Patient-Reported Outcomes of Swallowing Following Intensity Modulated Proton Therapy for Oropharyngeal Cancer, 2020-04-21

• Radiation-Related Alterations of Taste Function in Patients With Head and Neck Cancer: a Systematic Review, 2018-11-09

• Outcomes after salvage for HPV-positive recurrent oropharyngeal cancer treated with primary radiation, 2020-12-22

• Long-Term Outcomes Following Multi-Disciplinary Management of T3 Larynx Squamous Cell Carcinomas: Modern Therapeutic Approaches Improve Functional Outcomes and Survival, 2016-07-28

• Contemporary prostate cancer treatment choices in multidisciplinary clinics referenced to national trends, 2019-11-19

• Patient Reported Dry Mouth: Instrument Comparison and Model Performance for Correlation with Quality of Life in Head and Neck Cancer Survivors, 2017-12-08

• The Emerging Potential of Multi-Ion Radiotherapy, 2021-02-22

• Evaluation of the MIM Symphony treatment planning system for low-dose-rate- prostate brachytherapy, 2015-09-08

• Activity-Based Costing of Intensity-Modulated Proton versus Photon Therapy for Oropharyngeal Cancer, 2021-06-25

• COTI-2, a novel thiosemicarbazone derivative, exhibits antitumor activity in HNSCC through p53-dependent and -independent mechanisms, 2019-07-15

• A prospective parallel design study testing non-inferiority of customized oral stents made using 3D printing or manually fabricated methods, 2020-04-13

• Magnetic Resonance Imaging of Glucose Uptake and Metabolism in Patients with Head and Neck Cancer, 2016-07-27

• Combined inhibition of Rad51 and Wee1 enhances cell killing in HNSCC through induction of apoptosis associated with excessive DNA damage and replication stress, 2021-05-04

• Multiple-CT optimization: an adaptive optimization method to account for anatomical changes in intensity-modulated proton therapy for head and neck cancers, 2019-09-26

• The Biological Basis for Enhanced Effects of Proton Radiation Therapy Relative to Photon Radiation Therapy for Head and Neck Squamous Cell Carcinoma, 2021-06-25

• Multi-field Optimization Intensity-Modulated Proton Therapy for Head and Neck Tumors - A Translation to Practice, 2014-05-24

• Cognitive Function and Patient Reported Memory Problems Following Radiation Therapy for Cancers at the Skull Base: A Cross-sectional Survivorship Study Using the Telephone Interview for Cognitive Status (TICS) and the MD Anderson Symptom Inventory-Head and Neck Module (MDASI-HN), 2017-08-01

• A methodology to investigate the impact of image distortions on the radiation dose when using magnetic resonance images for planning, 2018-04-05

• Estimating PTV margins in head and neck stereotactic ablative radiation therapy (SABR) through target site analysis of positioning and intrafractional accuracy, 2019-09-30

• Changes in Apparent Diffusion Coefficient (ADC) in Serial Weekly MRI during Radiotherapy in Patients with Head and Neck Cancer: Results from the PREDICT-HN Study, 2022-08-31

• Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer, 2019-08-16

• Creating customized oral stents for head and neck radiotherapy using 3D scanning and printing, 2019-08-19

• Pulse sequence considerations for simulation and post-implant dosimetry of prostate brachytherapy, 2017-01-04

• Proton Therapy for Major Salivary Gland Cancer: Clinical Outcomes, 2021-06-25

• Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets, 2020-11-10

• Costs and Complications After a Diagnosis of Prostate Cancer Treated With Time-Efficient Modalities: An Analysis of National Medicare Data, 2020-04-13

• A Biodistribution and Toxicity Study of Cobalt Dichloride-N-Acetyl Cysteine (C4) as an Implantable MRI Marker for Prostate Cancer Treatment, 2012-10-22

• Quantifying the accuracy of deformable image registration for cone-beam computed tomography with a physical phantom WUet al., 2019-09-21

• Intensity modulated proton arc therapy via geometry-based energy selection for ependymoma, 2023-03-13

• Caspase-8 loss radiosensitizes head and neck squamous cell carcinoma to SMAC mimetic-induced necroptosis, 2020-12-03

• A Multidisciplinary Orbit-Sparing Treatment Approach That Includes Proton Therapy for Epithelial Tumors of the Orbit and Ocular Adnexa, 2015-08-07

• Prognostic significance of pre-treatment neutrophil-to-lymphocyte ratio (NLR) in patients with oropharyngeal cancer treated with radiotherapy, 2020-10-14

• A single-field integrated boost treatment planning technique for spot scanning proton therapy, 2014-09-11

• Predicting treatment Response based on Dual assessment of magnetic resonance Imaging kinetics and Circulating Tumor cells in patients with Head and Neck cancer (PREDICT-HN): matching ‘liquid biopsy' and quantitative tumor modeling, 2018-09-19

• Unilateral Radiation Therapy for Tonsillar Cancer: Treatment Outcomes in the Era of Human Papillomavirus, Positron-Emission Tomography, and Intensity Modulated Radiation Therapy, 2022-05-02

• Predictive performance of different NTCP techniques for radiation-induced esophagitis in NSCLC patients receiving proton radiotherapy, 2022-06-02

• Prospective Qualitative and Quantitative Analysis of Real-time Peer Review Quality Assurance Rounds Incorporating Direct Physical Examination for Head and Neck Cancer Radiation Therapy, 2016-11-19

• Metabolic Imaging as a Biomarker of Early Radiation Response in Tumors, 2015-07-31

• Utility of Surveillance Imaging in Patients with Head and Neck Cancer Treated with Definitive Radiotherapy, 2019-02-12

• Evaluation of the accuracy of deformable image registration on MRI with a physical phantom WU et al., 2019-12-06

• The Impact of Radiographic Retropharyngeal Adenopathy in Oropharyngeal Cancer, 2013-06-03

• Use of Androgen Deprivation Therapy with Prostate Brachytherapy, A Systematic Literature Review, 2017-01-16

• Radiation Therapy (with or without neck surgery) for Phenotypic HPV- associated Oropharyngeal Cancer, 2016-03-28

• Lymphopenia During Radiotherapy In Patients With Oropharyngeal Cancer, 2020-01-10

• Influence of Geography on Prostate Cancer Treatment, 2020-12-13

• Sexual Function and the use of Medical Devices or Drugs to Optimize Potency after Prostate Brachytherapy, 2012-01-31

• Surveillance Imaging for Patients with Head and Neck Cancer Treated with Definitive Radiotherapy: A Partially Observed Markov Decision Process Model, 2019-11-14

• Dose Escalation for Prostate Adenocarcinoma: A Long-Term Update on the Outcomes of a Phase III, Single Institution Randomized Clinical Trial, 2019-03-02

• Proton Beam Therapy for Head and Neck Carcinoma of Unknown Primary: Toxicity and Quality of Life, 2021-06-25

• Defining the Value Framework for Prostate Brachytherapy using Patient-Centered Outcome Metrics and Time-Driven Activity-Based Costing, 2016-02-23

• Deep learning application engine (DLAE): Development and integration of deep learning algorithms in medical imaging, 2019-10-29

• Highly-Conformal Reirradiation in Patients with Prior Oropharyngeal Radiation: Clinical Efficacy and Toxicity Outcomes, 2020-08-09

• Synchrotron-Based Pencil Beam Scanning Nozzle with an Integrated Mini-Ridge Filter: A Dosimetric Study to Optimize Treatment Delivery, 2017-12-13

• Toxicity Evaluation of a Novel Magnetic Resonance Imaging Marker, CoCl2-N-Acetylcysteine, in Rats, 2018-12-02

• Author Correction: Imaging and clinical data archive for head and neck squamous cell carcinoma patients treated with radiotherapy, 2018-11-27

• Minocycline for symptom reduction during radiation therapy for head and neck cancer: a randomized clinical trial, 2019-04-29

• Mixed Effect Modeling of Dose and Linear Energy Transfer Correlations With Brain Image Changes After Intensity Modulated Proton Therapy for Skull Base Head and Neck Cancer, 2021-06-19

• The Relationship Between Illness Uncertainty, Anxiety, Fear of Progression, and Quality of Life in Men With Favorable Risk Prostate Cancer Undergoing Active Surveillance, 2015-04-21

• Risk Groups of Laryngeal Cancer Treated with Chemoradiation According to Nomogram Scores - A Pooled Analysis of RTOG 0129 and 0522, 2021-02-25

• Permanent Prostate Brachytherapy Post-Implant MRI Dosimetry Using Positive Contrast MRI Markers, 2017-05-10

• Work Outcomes after Intensity-Modulated Proton Therapy (IMPT) versus Intensity-Modulated Photon Therapy (IMRT) for Oropharyngeal Cancer, 2021-06-25

• Outcomes and patterns of radiation associated brain image changes after proton therapy for head and neck skull base cancers, 2020-07-15

• Significance of Negative Posttreatment 18-FDG PET/CT Imaging in Patients With p16/HPV-Positive Oropharyngeal Cancer, 2018-06-28

• Preoperative treatment planning with intraoperative optimization can achieve consistent high-quality implants in prostate brachytherapy, 2012-05-03

• Comparing Intensity-Modulated Proton Therapy with Intensity-Modulated Photon Therapy for Oropharyngeal Cancer: The Journey From Clinical Trial Concept to Activation, 2018-02-11

• Reactive Oxygen Species Generation in Human Cells by a Novel Magnetic Resonance Imaging Contrast Agent, 2018-03-26

• Fully Balanced SSFP Without an Endorectal Coil for Postimplant QA of MRI-Assisted Radiosurgery (MARS) of Prostate Cancer: A Prospective Study, 2020-09-24

• The influence of radiation dose on taste impairment in a prospective observational study cohort of oropharyngeal cancer patients, 2022-01-21

• PTCOG Head and Neck Subcommittee Consensus Guidelines on Particle Therapy for the Management of Head and Neck Tumors, 2021-06-25

• Intensity Modulated Proton Therapy (IMPT) - The Future of IMRT for Head and Neck Cancer, 2018-11-21

• The Role of Particle Therapy in Adenoid Cystic Carcinoma and Mucosal Melanoma of the Head and Neck, 2021-06-25

• Knife or Needles? A Cohort Analysis of Outcomes after Radical Prostatectomy or Brachytherapy for Men with Low- or Intermediate-Risk Adenocarcinoma of the Prostate, 2012-06-21

• Stereotactic Body Ablative Radiotherapy for Reirradiation of Small Volume Head and Neck Cancers is Associated with Prolonged Survival: A Large, Single Institution, Modern Cohort Study, 2021-07-16

• Intensity-Modulated Proton Therapy (IMPT) versus Intensity-Modulated Photon Radiotherapy (IMRT) for Oropharyngeal Cancer: First Comparative Results of Patient-Reported Outcomes, 2016-02-18

• High Symptom Burden Prior to Radiation Therapy for Head and Neck Cancer: A Patient-Reported Outcomes Study, 2012-11-20

• Lyman-Kutcher-Burman normal tissue complication probability modeling for radiation-induced esophagitis in non-small cell lung cancer patients receiving proton radiotherapy, 2020-04-30

• PSA RESPONSE TO NEOADJUVANT ANDROGEN DEPRIVATION THERAPY IS A STRONG INDEPENDENT PREDICTOR OF SURVIVAL IN HIGH-RISK PROSTATE CANCER IN THE DOSE-ESCALATED RADIATION THERAPY ERA, 2012-10-23

• Intensity-modulated proton therapy for oropharyngeal cancer reduces rates of late xerostomia, 2021-04-08

• Quantitative Pretreatment Computerized Tomographic Volumetry is Associated with Oncologic Outcomes in Patients with T4a Squamous Carcinoma of the Larynx, 2017-05-02

• Nomogram for predicting symptom severity during radiation therapy for head and neck cancer, 2014-08-07

• Proton Therapy for Head and Neck Cancer: A 12-Year, Single-Institution Experience, 2021-06-25

• An MRI-Based Dose-Response Analysis of Urinary Sphincter Dose and Urinary Morbidity after Brachytherapy for Prostate Cancer in a Phase II Prospective Trial, 2013-03-01

• Beam path toxicity in candidate organs-at-risk: Assessment of radiation emetogenesis for patients receiving head and neck intensity modulated radiotherapy, 2014-04-17

• Impact of RBE variations on risk estimates of temporal lobe necrosis in patients treated with intensity modulated proton therapy for head and neck cancer, 2021-09-17

• MRI characterization of cobalt dichloride-N-acetyl cysteine (C4) contrast agent marker for prostate brachytherapy, 2014-04-28

• Radiographic Retropharyngeal Lymph Node Involvement in HPV-Associated Oropharyngeal Carcinoma: Patterns of Involvement and Impact on Patient Outcomes, 2019-01-08

• Long-term patient reported outcomes following radiation therapy for oropharyngeal cancer: cross-sectional assessment of a prospective symptom survey in patients =65 years old, 2017-09-09

• Cost-Effectiveness Models of Proton Therapy for Head and Neck: Evaluating Quality and Methods to Date, 2021-06-25

• Patient-Reported Outcomes after Intensity-Modulated Proton Therapy for Oropharynx Cancer, 2021-06-25

• Financial Toxicity in Head and Neck Cancer Patients Treated With Proton Therapy, 2021-06-25

• Outcomes of oral cavity cancer patients treated with surgery followed by postoperative intensity modulated radiation therapy, 2017-07-16

• Association of Sociodemographic and Health-Related Factors With Receipt of Nondefinitive Therapy Among Younger Men With High-Risk Prostate Cancer Factors Associated With Receipt of Nondefinitive Therapy for Prostate Cancer, 2020-03-19

• Evaluation of the high definition field of view option of a large-bore computed tomography scanner for radiation therapy simulation, 2020-03-26

• Conditional Survival Among Patients With Oropharyngeal Cancer Treated With Radiation Therapy and Alive Without Recurrence 5 Years After Diagnosis, 2020-12-11

• Communicating Value in Healthcare using Radar Charts: A Case Study of Prostate Cancer, 2016-08-30

• Comprehensive Quantitative Evaluation of Variability in MR-guided Delineation of Oropharyngeal Gross Tumor Volumes and High-risk Clinical Target Volumes: An R-IDEAL Stage 0 Prospective Study, 2022-02-04

• Magnetic Resonance Imaging of Swallowing-Related Structures in Nasopharyngeal Carcinoma Patients Receiving IMRT: Longitudinal Dose-Response Characterization of Quantitative Signal Kinetics, 2016-01-28

• Intravoxel Incoherent Motion Imaging Kinetics during Chemoradiotherapy for Human Papillomavirus-Associated Squamous Cell Carcinoma of the Oropharynx: Preliminary Results from a Prospective Pilot Study, 2015-10-09

• Characteristics and kinetics of cervical lymph node regression after radiation therapy for human papillomavirus-associated oropharyngeal carcinoma: Quantitative image analysis of post-radiotherapy response, 2014-11-28

• Quality of Life and Toxicity from Passively Scattered and Spot-Scanning Proton Beam Therapy for Localized Prostate Cancer, 2013-10-15

• Clinical Use of Magnetic Resonance Imaging Across the Prostate Brachytherapy Workflow, 2017-01-30

• Communicating Value: Use of a Novel Framework in the Assessment of an Enhanced Recovery Initiative, 2021-01-01

• Intensity-modulated proton therapy and osteoradionecrosis in oropharyngeal cancer, 2017-05-23

• Endorectal MRI for predicting pathologic T3 disease in Gleason score 7 prostate cancer: Implications for prostate brachytherapy, 2012-06-05

• Characterization of a new physical phantom for testing rigid and deformable image registration, 2018-12-23

• Proton Radiotherapy to Reduce Late Complications in Childhood Head and Neck Cancers, 2021-06-25

• Three-Dimensional Imaging Assessment of Anatomic Invasion and Volumetric Considerations for Chemo/Radiotherapy-Based Laryngeal Preservation in T3 larynx Cancer, 2018-02-10

• Patterns of locoregional failure following post-operative intensity-modulated radiotherapy to oral cavity cancer: quantitative spatial and dosimetric analysis using a deformable image registration workflow, 2017-08-15

• Data from a terminated study on iron oxide nanoparticle magnetic resonance imaging for head and neck tumors, 2020-02-21

• The Potential of Heavy-Ion Therapy to Improve Outcomes for Locally Advanced Non-Small Cell Lung Cancer, 2017-09-05

• Quality Comparison between 3-dimensional T2-weighted SPACE and 2-dimensional T2-weighted turbo spin echo magnetic resonance images for the brachytherapy planning evaluation of prostate and periprostatic anatomy, 2020-05-10

• Xerostomia-related quality of life for patients with oropharyngeal carcinoma treated with proton therapy, 2019-08-17

• Disease reclassification risk with stringent criteria and frequent monitoring in men with favorable-risk prostate cancer undergoing active surveillance, 2015-07-04

• Risk of second primary malignancies in head and neck cancer patients treated with definitive radiotherapy, 2019-09-27

• Prospective Observer and Software-based Assessment of Magnetic Resonance Imaging Quality in Head and Neck Cancer: Should Standard Positioning and Immobilization Be Required for Radiotherapy Applications?, 2014-12-17