Dr. Shernan Holtan, MD

• Hematology

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• University Of Nebraska Medical Center College Of Medicine

  Medical School, 2004

• Solid Organ Transplant Graft-Versus-Host Disease in a Kidney/Pancreas Transplant Patient: Use of Chimerism Testing and a Rare Presentation of Cutaneous GVHD, 2022-03-09

• Marrow damage and hematopoietic recovery following allogeneic bone marrow transplantation for acute leukemias: effect of radiation dose and conditioning regimen, 2015-11-30

• Gut microbiota response to antibiotics is personalized and depends on baseline microbiota, 2021-10-27

• Low EGF in Myeloablative Allotransplantation: Association with Severe Acute GVHD in BMT CTN 0402, 2017-06-05

• Sirolimus and Mycophenolate Mofetil as Calcineurin Inhibitor-Free GVHD Prophylaxis for RIC Umbilical Cord Blood Transplantation, 2016-08-09

• Immune Reactivation by Cell-Free Fetal DNA in Healthy Pregnancies Re-Purposed to Target Tumors: Novel Checkpoint Inhibition in Cancer Therapeutics, 2015-08-26

• 75200 Fecal Microbiota Transplantation to Prevent Infections in Patients with Acute Myeloid Leukemia: A Double-Blind Randomized Placebo-Controlled Phase 2 Clinical Trial, 2021-03-30

• Outcomes and predictors of response in steroid-refractory acute graft-versus-host disease: single-center results from a cohort of 203 patients, 2019-07-17

• Human effectors of acute and chronic GVHD overexpress CD83 and predict mortality, 2023-03-14

• Placental Growth Factor: What Hematologists Need to Know, 2016-08-27

• National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IIa. The 2020 Clinical Implementation and Early Diagnosis Working Group Report, 2021-04-09

• Circulating Angiogenic Factors Associated with Response and Survival in Patients with Acute Graft-Versus-Host Disease: Results from BMT CTN 0302 and 0802, 2015-03-07

• PlGF enhances TLR-dependent inflammatory responses in human mononuclear phagocytes, 2017-06-20

• High incidence of thromboembolism in patients with chronic GVHD: association with severity of GVHD and donor-recipient ABO blood group, 2021-05-18

• Hematopoietic Cell Transplant-Related Toxicities and Mortality in Frail Recipients, 2019-08-05

• Whole-Body Distribution of Leukemia and Functional Total Marrow Irradiation Based on FLT-PET and Dual-Energy CT, 2017-09-26

• Life-Threatening Hypertriglyceridemia in a Patient on Ruxolitinib and Sirolimus for Chronic Graft-versus-Host Disease, 2018-11-04

• Pediatric acute GVHD: clinical phenotype and response to upfront steroids, 2019-09-02

• Pacritinib combined with sirolimus and low-dose tacrolimus for GVHD prevention after allogeneic hematopoietic cell transplantation: Preclinical and Phase I trial results, 2021-03-22

• Perspectives of cancer patients and their health during the COVID-19 pandemic, 2020-10-30

• Donor and Recipient Plasma Follistatin Levels are Associated with Acute Graft-versus-Host Disease in Blood and Marrow Transplant Clinical Trials Network 0402, 2017-10-23

• Dynamic Graft-versus-Host Disease-Free, Relapse-Free Survival: Multistate Modeling of the Morbidity and Mortality of Allotransplantation, 2019-05-22

• Loss of microbiota-derived protective metabolites after neutropenic fever, 2022-04-15

• Impact of clinical factors and allograft leukocyte content on post-transplant lymphopenia, monocytopenia, and survival in patients undergoing allogeneic peripheral blood haematopoietic cell transplant, 2014-09-01

• Effect of COVID-19 precautions on the gut microbiota and nosocomial infections GUT MICROBES, 2021-06-16

• Monocyte subpopulation recovery as predictors of hematopoietic cell transplantation outcomes, 2019-01-06

• Follistatin and Soluble Endoglin Predict 1-year Non-Relapse Mortality after Allogeneic Hematopoietic Cell Transplant, 2019-11-10

• Fetal sex-based differences in maternal hormones, angiogenic factors, and immune mediators during pregnancy and the postpartum period, 2014-08-04

• Peripheral Blood versus Bone Marrow from Unrelated Donors: Bone Marrow allografts have improved Long-term Overall and Graft-versus-Host Disease, Relapse-Free Survival, 2018-10-03

• Circulating bacterial DNA and neutropenic fever during antileukaemia chemotherapy, 2020-07-26

• Amphiregulin in intestinal acute graft-versus-host disease: a possible diagnostic and prognostic aid, 2018-11-13

• Prevention of graft versus host disease with Hematopoietic Cell Transplantation with Reduced Intensity Conditioning-a comparison of three prophylaxis regimens (tacrolimus/mycophenolate mofetil/cyclophosphamide, tacrolimus/methotrexate/bortezomib or tacrolimus/methotrexate/maraviroc) versus tacrolimu, 2019-04-09

• Early assessment of dosimetric and biological differences of total marrow irradiation versus total body irradiation in rodents, 2017-08-01

• PHASE I TRIAL OF ALT-803, A NOVEL RECOMBINANT INTERLEUKIN-15 COMPLEX, IN PATIENTS WITH ADVANCED SOLID TUMORS, 2018-07-25

• Graft-versus-host disease: teaching old drugs new tricks at less cost, 2023-08-03

• Compilation of longitudinal gut microbiome, serum metabolome, and clinical data in acute myeloid leukemia, 2022-08-02

• Galectin-9 modulates immunity by promoting Th2/M2 differentiation and impacts survival in patients with metastatic melanoma, 2018-04-25

• Growth Modeling of the Maternal Cytokine Milieu throughout Normal Pregnancy: Macrophage-Derived Chemokine Decreases as Inflammation/Counterregulation Increases, 2015-03-17

• A refined risk score for acute GVHD that predicts response to initial therapy, survival and transplant-related mortality, 2015-01-10

• Pre-transplant serum citrulline predicts acute graft-versus-host disease, 2018-07-07

• Vancomycin-resistance gene cluster,vanC, in the gut microbiome of acute leukemia patients undergoing intensive chemotherapy, 2019-10-10

• Outcomes of chronic graft-versus-host disease following matched sibling donor versus umbilical cord blood transplant, 2021-01-08

• Use of Potentially Inappropriate Medications in Older Allogeneic Hematopoietic Cell Transplantation Recipients, 2020-09-10

• Obesity Induces Gut Microbiota Alterations and Augments Acute Graft-Versus-Host Disease After Allogeneic Stem Cell Transplantation, 2020-11-25

• Angiogenic Factors and Inflammation in Steroid-Refractory Acute Graft-Versus-Host Disease, 2015-06-09

• Monosomal karyotype at the time of diagnosis or transplantation predicts outcomes of Allogeneic Hematopoietic Cell Transplantation in Myelodysplastic Syndrome, 2015-01-22

• Health-Related Quality of Life Outcomes in Older Hematopoietic Cell Transplant Survivors, 2022-11-23

• Dose Escalation of Total Marrow Irradiation in High-Risk Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation, 2017-04-07

• Dysbiosis patterns during re-induction/salvage versus induction chemotherapy for acute leukemia, 2019-04-15

• Antibiotic practice patterns in hematopoietic cell transplantation: A survey of Blood and Marrow Transplant Clinical Trials Network centers, 2018-09-09