Dr. Scott Solomon, MD

• Internal Medicine

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• Harvard Medical School

  Medical School, 1986

• Sacubitril/Valsartan: Neprilysin inhibition 5 Years after PARADIGM-HF, 2022-02-03

• Angiotensin Receptor-Neprilysin Inhibitor Therapy Reverses Pulmonary Hypertension in End-Stage Heart Failure Patients Awaiting Transplantation, 2020-02-14

• C-Reactive Protein and Risk of ESRD: Results From the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT), 2016-09-16

• Left ventricular mechanical function: clinical correlates, heritability, and association with parental heart failure, 2014-12-01

• Ideal Cardiovascular Health During Adult Life and Cardiovascular Structure and Function Among the Elderly, 2015-09-08

• Specific Electrocardiograph Intervals Predict Hospitalization with Atrial Fibrillation in those with Chronic Kidney Disease, 2021-05-05

• Effect of Dapagliflozin on Outpatient Worsening of Patients With Heart Failure and Reduced Ejection Fraction A Prespecified Analysis of DAPA-HF, 2020-09-04

• Prevalence and prognostic importance of precipitating factors leading to heart failure hospitalization: Recurrent hospitalizations and mortality, 2017-09-04

• Declining Lung Function and Cardiovascular Risk: The Atherosclerosis Risk in Communities (ARIC) Study, 2018-09-04

• Effects of sacubitril/valsartan on glycemia in patients with diabetes and heart failure: the PARAGON-HF and PARADIGM-HF trials, 2022-06-18

• Echocardiographic Measures of Cardiac Structure and Function Are Associated with Risk of Atrial Fibrillation in Blacks: The Atherosclerosis Risk in Communities (ARIC) Study, 2014-10-16

• Estimating the Lifetime Benefits of Treatments for Heart Failure, 2020-12-01

• Feasibility of randomizing Danish citizens aged 65-79 years to high-dose quadrivalent influenza vaccine vs. standard-dose quadrivalent influenza vaccine in a pragmatic registry-based setting: rationale and design of the DANFLU-1 Trial, 2022-04-21

• Sex-Specific Association of Sleep Apnea Severity with Subclinical Myocardial Injury, Ventricular Hypertrophy, and Heart Failure Risk in a Community Dwelling Cohort: The Atherosclerosis Risk in Communities-Sleep Heart Health Study, 2015-08-27

• The Prognostic Importance of Changes in Cardiac Structure and Function in Heart Failure with Preserved Ejection Fraction and the Impact of Spironolactone, 2015-10-16

• Kidney Function and Outcomes in Patients Hospitalized With Heart Failure, 2021-05-11

• Impact of Sacubitril/Valsartan compared to Ramipril on cardiac structure and function following acute myocardial infarction: The PARADISE-MI Echocardiographic Sub-Study, 2022-09-09

• Developing and validating models to predict sudden death and pump failure death in patients with heart failure and preserved ejection fraction, 2020-12-10

• Ferritin levels and risk of heart failure - the Atherosclerosis Risk in Communities Study, 2016-12-14

• Ultrasound imaging of congestion in heart failure: examinations beyond the heart, 2020-11-23

• Physical Activity and Prognosis in the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) Trial, 2017-06-21

• Evaluation of Multiple Biomarkers of Cardiovascular Stress for Risk Prediction and Guiding Medical Therapy in Patients with Stable Coronary Disease, 2011-12-16

• CVOT Summit 2022 Report: new cardiovascular, kidney, and glycemic outcomes, 2023-03-16

• Cardiovascular implications of COVID-19 versus influenza infection: a review, 2020-12-18

• Left Atrial Structure and Function Across the Spectrum of Cardiovascular Risk in the Elderly: The Atherosclerosis Risk in Communities (ARIC) Study, 2016-06-16

• Alternatives to hazard ratios for comparing efficacy or safety of therapies in noninferiority studies, 2015-07-21

• 6-Year Change in High Sensitivity Cardiac Troponin-T and Risk for Subsequent Coronary Heart Disease, Heart Failure and Death, 2016-08-01

• Dapagliflozin in heart failure with improved ejection fraction: a prespecified analysis of the DELIVER trial, 2022-12-15

• Pre-existing traits associated with Covid-19 illness severity, 2020-07-23

• Challenges of Cardio-kidney Composite Outcomes in Large-Scale Clinical Trials, 2021-01-07

• Angiotensin-Neprilysin Inhibition and Renal Outcomes Across the Spectrum of Ejection Fraction in Heart Failure, 2022-01-18

• Relation Between Alcohol Consumption and Cardiac Structure and Function in the Elderly: The Atherosclerosis Risk in Communities (ARIC) Study, 2015-04-17

• Prognostic Importance of Left Ventricular Mechanical Dyssynchrony in Heart Failure With Preserved Ejection Fraction, 2017-03-21

• Widening Racial Differences in Risks for Coronary Heart Disease, 2018-03-13

• Dapagliflozin and Diuretic Use in Patients With Heart Failure and Reduced Ejection Fraction in DAPA-HF, 2020-07-16

• Hemodynamic Correlates of Blood Pressure in Older Adults: The ARIC Study, 2016-08-20

• Relationship Between Timing of Trial Randomization, Protocol Completion, and Clinical Outcomes Among Patients Hospitalized for Heart Failure: From the ASTRONAUT Trial, 2018-11-11

• Prognostic importance of temporal changes in resting heart rate in heart failure and preserved ejection fraction from the TOPCAT study, 2017-10-11

• Application of Diagnostic Algorithms for Heart Failure with Preserved Ejection Fraction to the Community: The ARIC Study, 2020-06-10

• Contemporary Assessment of Left Ventricular Diastolic Function in Older Adults: The Atherosclerosis Risk In Communities Study, 2016-12-07

• Optimal Background Pharmacological Therapy for Heart Failure Patients in Clinical Trials, 2022-02-08

• Weight History and Subclinical Myocardial Damage, 2017-11-20

• The Associations between Left Ventricular structure, function, and Cerebral Amyloid: The ARIC-PET study, 2019-10-10

• Influence of atrial fibrillation on post-discharge natriuretic peptide trajectory and clinical outcomes among patients hospitalized for heart failure: insights from the ASTRONAUT trial, 2016-10-17

• A formal validation of a deep learning-based automated workflow for the interpretation of the echocardiogram, 2022-11-09

• A Phase 1 Dose-Escalation Study of the Cardiac Myosin Inhibitor Aficamten in Healthy Participants, 2022-08-10

• Genetic Variants inSGLT1, Glucose Tolerance, and Cardiometabolic Risk, 2018-10-09

• Pulmonary vascular dysfunction among people aged over 65 years in the community in the Atherosclerosis Risk In Communities (ARIC) Study: A cross-sectional analysis, 2020-10-15

• Heart Failure Endpoints in Cardiovascular Outcome Trials of SGLT2 inhibitors in Patients with Type 2 Diabetes: A Critical Evaluation of Clinical and Regulatory Issues, 2019-12-16

• American Heart Association's Life's Simple 7: Avoiding Heart Failure and Preserving Cardiac Structure and Function, 2015-04-20

• Utilizing the integrated difference of two survival functions to quantify the treatment contrast for designing, monitoring and analyzing a comparative clinical study, 2012-08-22

• Temporal Trends in the Population Attributable Risk for Cardiovascular Disease: The Atherosclerosis Risk in Communities Study, 2014-08-11

• Spironolactone Metabolites in TOPCAT - New Insights into Regional Variation, 2017-04-27

• Iron Deficiency in Heart Failure and Effect of Dapagliflozin: Findings From DAPA-HF, 2022-08-16

• Quantification of pleural effusions on thoracic ultrasound in acute heart failure, 2020-01-24

• Dapagliflozin across the range of ejection fraction in patients with heart failure: a patient-level, pooled meta-analysis of DAPA-HF and DELIVER, 2022-08-27

• ASSESSMENT OF MYOCARDIAL VIABILITY AND LEFT VENTRICULAR FUNCTION IN PATIENTS SUPPORTED BY A LEFT VENTRICULAR ASSIST DEVICE, 2014-01-27

• Age- and Sex-based Reference Limits and Clinical Correlates of Myocardial Strain and Synchrony: The Framingham Heart Study, 2013-08-05

• Association of Undifferentiated Dyspnea in Late Life With Cardiovascular and Noncardiovascular Dysfunction A Cross-sectional Analysis From the ARIC Study Association of Undifferentiated Dyspnea With Cardiovascular Dysfunction, 2019-06-14

• Influence of Cigarette Smoking on Cardiac Biomarkers: the Atherosclerosis Risk in Communities (ARIC) Study, 2016-03-30

• Renin-angiotensin system blockers, risk of SARS-CoV-2 infection and outcomes from CoViD-19: systematic review and meta-analysis, 2022-02-16

• Plasma renin activity, response to aliskiren, and clinical outcomes in patients hospitalized for heart failure: the ASTRONAUT trial, 2017-11-16

• Change in Hemoglobin Trajectory and Darbepoetin Dose Approaching End-Stage Renal Disease: Data from the TREAT trial, 2017-12-14

• Reproducibility of Speckle-Tracking Based Strain Measures of Left Ventricular Function in a Community-Based Study, 2013-08-14

• Insulin Resistance and Incident Heart Failure The ARIC Study (Atherosclerosis Risk in Communities), 2014-01-10

• Patient Characteristics, Clinical Outcomes, and Effect of Dapagliflozin in Relation to Duration of Heart Failure: Is It Ever Too Late to Start a New Therapy?, 2020-11-09

• Association of Heart Failure Subtypes and Atrial fibrillation: Data from the Atherosclerosis Risk in Communities (ARIC) Study, 2021-07-08

• Cardiac Structure and Function Across the Spectrum of Aldosteronism: The Atherosclerosis Risk in Communities Study, 2022-05-18

• Rationale and Design of a Multicenter Echocardiographic Study to Assess the Relationship between Cardiac Structure and Function and Heart Failure Risk in a Biracial Cohort of Community Dwelling Elderly Persons: The Atherosclerosis Risk in Communities (ARIC) Study, 2013-11-08

• Race-related differences in left ventricular structural and functional remodeling in response to increased afterload: the Atherosclerosis Risk in Communities Study, 2016-12-21

• Association of High-Sensitivity Cardiac Troponin T and Natriuretic Peptide With Incident ESRD: The Atherosclerosis Risk in Communities (ARIC) Study, 2014-10-23

• Within trial comparison of survival time projections from short-term follow-up with long-term follow-up findings J.P. Ferreiraet al., 2022-07-07

• Multiple Comorbidities and Response to Cardiac Resynchronization Therapy: MADIT-CRT Long-Term Follow-Up, 2017-05-16

• Dapagliflozin and atrial fibrillation in heart failure with reduced ejection fraction: insights from DAPA-HF J.H. Buttet al., 2021-11-24

• Predicting risk in patients hospitalized for acute decompensated heart failure and preserved ejection fraction: The Atherosclerosis Risk in Communities Study Heart Failure Community Surveillance, 2019-01-21

• Cause of Death in Patients With Diabetic CKD Enrolled in the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT), 2015-04-29

• Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study, 2022-02-13

• Effect of P2Y12 Inhibitors on Organ Support-Free Survival in Critically Ill Patients Hospitalized for COVID-19 A Randomized Clinical Trial P2Y12 Inhibitors and Survival in Critically Ill Patients With COVID-19, 2023-05-25

• Age and Gender-Related Influences on Left Ventricular Mechanics in Elderly Individuals Free of Prevalent Heart Failure: The Atherosclerosis Risk in Communities Study, 2016-12-31

• Association of Hyper-polypharmacy With Clinical Outcomes in Heart Failure With Preserved Ejection Fraction, 2021-10-22

• Pre-discharge and early post-discharge troponin elevation among patients hospitalized for heart failure with reduced ejection fraction: insights from the ASTRONAUT trial, 2017-10-17

• Smoking and Cardiac Structure and Function in the Elderly: The Atherosclerosis Risk in Communities (ARIC) Study, 2016-07-28

• Health-related quality of life in acute heart failure: association between patient-reported symptoms and markers of congestion, 2022-10-14

• Heart Failure Risk Across the Spectrum of Ankle-Brachial Index: The Atherosclerosis Risk in Communities Study, 2014-09-03

• Association of Weight and Body Composition on Cardiac Structure and Function in the Atherosclerosis Risk in Communities (ARIC) Study, 2016-08-03

• Outcomes of Patients with Anemia and Acute Decompensated Heart Failure with Preserved versus Reduced Ejection Fraction (From the ARIC Study Community Surveillance), 2014-09-28

• Blood pressure and mortality in patients with type 2 diabetes and a recent coronary event in the ELIXA trial, 2020-10-12

• The prognostic significance of cardiac structure and function in atrial fibrillation: the ENGAGE AF-TIMI 48 Echocardiographic Substudy, 2016-04-20

• Association of Post-vaccination Adverse Reactions After Influenza Vaccine with Mortality and Cardiopulmonary Outcomes in Patients with High-risk Cardiovascular Disease: The INVESTED Trial., 2022-11-06

• Prognostic Utility of Secretory Phospholipase A2in Patients with Stable Coronary Artery Disease, 2011-07-22

• Association of Influenza Vaccination With Cardiovascular Risk A Meta-analysis Influenza Vaccination and Cardiovascular Risk, 2022-04-29

• High-sensitivity troponin I and incident coronary events, stroke, heart failure hospitalization, and mortality in the Atherosclerosis Risk in Communities (ARIC) Study, 2019-04-29

• Risk Factors for Atrial Fibrillation in Patients with Normal versus Dilated Left Atria (from the Atherosclerosis Risk in Communities [ARIC] Study), 2014-08-18

• The Design of the Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy (VANISH) Trial, 2017-02-16

• Effects of dapagliflozin in heart failure with reduced ejection fraction and chronic obstructive pulmonary disease: an analysis of DAPA-HF P. Dewanet al., 2021-01-18

• Utility of the Cardiovascular Physical Examination and Impact of Spironolactone in Heart Failure with Preserved Ejection Fraction: TOPCAT, 2019-06-21

• Effects of Dapagliflozin on Symptoms, Function, and Quality of Life in Patients With Heart Failure and Reduced Ejection Fraction Results From the DAPA-HF Trial, 2019-11-17

• Retinopathy, Neuropathy, and Subsequent Cardiovascular Events in Patients with Type 2 Diabetes and Acute Coronary Syndrome in the ELIXA: The Importance of Disease Duration, 2018-12-16

• Computational Modeling Studies of the Roles of Left Ventricular Geometry, Afterload, and Muscle Contractility on Myocardial Strains in Heart Failure with Preserved Ejection Fraction, 2021-04-29

• Heart Failure with Preserved Ejection Fraction in African-Americans - The Atherosclerosis Risk in Communities (ARIC) Study, 2013-04-01

• Levels and Change in Galectin-3 and Association With Cardiovascular Events: The ARIC Study, 2020-06-23

• Baseline characteristics of the Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy cohort, 2019-12-09

• Refining Prediction of Atrial Fibrillation-Related Stroke Using the P2-CHA2DS2-VASc Score: the Atherosclerosis Risk in Communities (ARIC) study and Multi-Ethnic Study of Atherosclerosis (MESA), 2019-01-08

• Coronary microvascular dysfunction, left ventricular remodeling and clinical outcomes in patients with chronic kidney impairment, 2019-11-29

• Race and Gender-Based Differences in Cardiac Structure and Function and Risk of Heart Failure, 2022-02-01

• An NPPB Promoter Polymorphism Associated With Elevated N-Terminal pro-B-Type Natriuretic Peptide and Lower Blood Pressure, Hypertension, and Mortality, 2017-03-24

• On the Restricted Mean Survival Time Curve in Survival Analysis, 2015-08-24

• Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study P. Welsh et al., 2017-09-27

• Response to Letter Regarding Article "High-Sensitivity Troponin I and Incident Coronary Events, Stroke, Heart Failure Hospitalization, and Mortality in the ARIC Study”, 2019-11-11

• Left atrial structure and function and the risk of death or heart failure in atrial fibrillation, 2019-11-27

• Racial Disparities in Risks of Stroke, 2017-05-25

• Global Electrical Heterogeneity Risk Score for Prediction of Sudden Cardiac Death in the General Population: The Atherosclerosis Risk in Communities (ARIC) and Cardiovascular Health (CHS) Studies, 2016-04-14

• Impact of sacubitril/valsartan versus ramipril on total heart failure events in the PARADISE-MI Trial, 2021-11-19

• B-type Natriuretic Peptide During Treatment with Sacubitril/Valsartan: the PARADIGM-HF Trial, 2019-03-04

• Lung ultrasound: monitoring congestion in patients with heart failure, 2019-11-08

• Quantifying Treatment Effects in Trials with Multiple Event-Time Outcomes, 2022-06-30

• Treatment of Anemia with Darbepoetin Prior to Dialysis Initiation and Clinical Outcomes - Analyses from the Trial to Reduce cardiovascular Events with Aranesp Therapy (TREAT), 2018-12-19

• Liver tests and outcomes in heart failure with reduced ejection fraction: findings from DAPA-HF C. Adamsonet al., 2022-08-22

• Influence of Prior Heart Failure Hospitalization on Cardiovascular Events in Patients with Reduced and Preserved Ejection Fraction, 2014-05-29

• Fibroblast Growth Factor-23, Cardiovascular Prognosis, and Benefit of Angiotensin-Converting Enzyme Inhibition in Stable Ischemic Heart Disease, 2014-04-09

• Temporal Association Among Influenza-Like Illness, Cardiovascular Events, and Vaccine Dose in Patients With High-Risk Cardiovascular Disease Secondary Analysis of a Randomized Clinical Trial Influenza-Like Illness, CV Events, and Vaccine Dose in CV Disease, 2023-09-14

• Prior Heart Failure Hospitalization, Clinical Outcomes, and Response to Sacubitril/Valsartan Compared with Valsartan in HFpEF, 2019-11-11

• Adiposity, body composition and ventricular-arterial stiffness in the elderly: the Atherosclerosis Risk in Communities Study, 2018-04-16

• Prevalence of Prediabetes and Undiagnosed Diabetes in Patients with HFpEF and HFrEF and Associated Clinical Outcomes, 2017-09-25

• Sex Differences in Characteristics, Outcomes and Treatment Response with Dapagliflozin across the Range of Ejection Fraction in Patients with Heart Failure: Insights from DAPA-HF and DELIVER, 2022-11-07

• Prognostic Value of Albuminuria and Influence of Spironolactone in Heart Failure with Preserved Ejection Fraction: The TOPCAT Trial, 2019-01-21

• Development and external validation of prognostic models to predict sudden and pump-failure death in patients with HFrEF from PARADIGM-HF and ATMOSPHERE, 2021-06-08

• Impaired Left Atrial Function in Heart Failure with Preserved Ejection Fraction, 2014-08-19

• Heart Failure Stages Among Older Adults in the Community: The Atherosclerosis Risk in Communities Study, 2016-11-23

• Endothelin-1, Outcomes in Patients With Heart Failure and Reduced Ejection Fraction, and Effects of Dapagliflozin: Findings From DAPA-HF, 2023-04-11

• The effect of statin therapy on heart failure events: a collaborative meta-analysis of unpublished data from major randomized trials, 2015-03-23

• Sex differences in congestive markers in patients hospitalized for acute heart failure C. Espersenet al., 2021-03-11

• Left Ventricular Ejection Time is an Independent Predictor of Incident Heart Failure in a Community based Cohort, 2017-09-04

• Differential Influence of Distinct Components of Increased Blood Pressure on Cardiovascular OutcomesR3, 2013-07-22

• Increased Risk of Stroke with Darbepoetin Alfa in Anaemic Heart Failure Patients with Diabetes and Chronic Kidney Disease, 2015-10-01

• Lung ultrasound in acute heart failure: Prevalence of pulmonary congestion and short- and long-term outcomes, 2021-08-25

• Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial, 2021-09-23

• Latent Pulmonary Vascular Disease May Alter the Response to Therapeutic Atrial Shunt Device in Heart Failure, 2022-03-31

• Risk of stroke in chronic heart failure patients with preserved ejection fraction, but without atrial fibrillation: analysis of the CHARM-Preserved and I-Preserve trials, 2016-11-13

• Application of the H2FPEF Score to a Global Clinical Trial of Patients with Heart Failure with Preserved Ejection Fraction: The TOPCAT Trial, 2019-07-22

• B-type natriuretic peptide and cardiac troponin I are associated with adverse outcomes in stable kidney transplant recipients, 2015-12-07

• Investigating the Role of Interventricular Interdependence in Development of Right Heart Dysfunction During LVAD Support: A Patient-Specific Methods-Based Approach, 2018-05-11

• The Prognostic Importance of Impaired Systolic Function in Heart Failure with Preserved Ejection Fraction and the Impact of Spironolactone, 2015-06-30

• Developing Therapies for Heart Failure with Preserved Ejection Fraction: Current State and Future Directions, 2014-05-02

• Retinal Vessel Calibers in Predicting Long-Term Cardiovascular Outcomes: The Atherosclerosis Risk in Communities Study, 2016-09-28

• Soluble Angiotensin-Converting Enzyme 2, Cardiac Biomarkers, Structure, and Function, and Cardiovascular Events (From the Atherosclerosis Risk in Communities Study), 2021-02-02

• Association of Mild Valvular Lesions With Long-term Cardiovascular Outcomes Among Black Adults Mild Valvular Lesions and Cardiovascular Outcomes Among Black Adults, 2022-05-12

• Reassessing the Role of Surrogate Endpoints in Drug Development for Heart Failure, 2018-09-04

• Canagliflozin and Heart Failure in Type 2 Diabetes Mellitus Results From the CANVAS Program, 2018-07-30

• Global Electrocardiographic Measures and Cardiac Structure and Function: The Atherosclerosis Risk in Communities (ARIC) Study, 2018-01-24

• High-Dose Influenza Vaccine to Reduce Clinical Outcomes in High Risk Cardiovascular Patients: Rationale and Design of the INVESTED Trial, 2018-05-23

• Lipoprotein (a) For Risk Assessment in Patients with Established Coronary Artery Disease, 2013-10-23

• Associations of Insulin Resistance with Systolic and Diastolic Blood Pressure: A Study from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), 2021-08-11

• Predictors of Heart Failure in Patients with Stable Coronary Artery Disease: A PEACE Study, 2009-04-14

• Influence of ejection fraction on cause-specific mortality in heart failure with preserved ejection fraction, 2017-10-25