Dr. Karen Lu, MD

• Gynecologic Oncology

• Obstetrics & Gynecology

*Healthgrades does not verify qualifications for medical specialties. Please verify your provider's specialty and qualifications directly with your provider and applicable medical board.

• Yale University

  Medical School, 1991

• Genotype inBRCA-associated Breast Cancers, 2012-12-10

• Body mass index and attitudes towards health behaviors among women with endometrial cancer before and after treatment, 2019-12-15

• PROGNOSTIC FACTORS IMPACTING SURVIVAL IN EARLY STAGE UTERINE CARCINOSARCOMA, 2018-11-08

• Timing of surgery in patients with partial response or stable disease after neoadjuvant chemotherapy for advanced ovarian cancer, 2021-04-16

• Sexual health of endometrial cancer survivors before and after a physical activity intervention: a retrospective cohort analysis, 2016-09-24

• PALB2,CHEK2andATMrare variants and cancer risk: data from COGS, 2016-09-05

• The Anterior Gradient Homolog 3 (AGR3) Gene Is Associated with Differentiation and Survival in Ovarian Cancer, 2011-03-10

• Diet, weight management, physical activity and Ovarian & Breast Cancer Risk in women withBRCA1/2pathogenic Germline gene variants: systematic review, 2020-03-07

• Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study, 2018-03-20

• TheFANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer, 2019-11-01

• Pathogenesis and Clinical Management of Uterine Serous Carcinoma, 2020-03-14

• Effect of an Enhanced Recovery After Surgery Program on Opioid Use and Patient-Reported Outcomes, 2018-10-16

• Recommendations and Choices for BRCA Mutation Carriers at Risk for Ovarian Cancer: A Complicated Decision, 2018-02-21

• National trends, outcomes, and costs of radiation therapy in the management of low- and high-intermediate risk endometrial cancer, 2019-07-17

• Factors Associated with Response to Neoadjuvant Chemotherapy in Advanced Stage Ovarian Cancer, 2021-04-07

• Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk, 2022-03-22

• Impact of body mass index and operative approach on surgical morbidity and costs in women with endometrial carcinoma and hyperplasia, 2017-01-26

• Genetic polymorphisms and endometrial cancer risk, 2017-05-07

• Neoadjuvant chemotherapy in elderly women with ovarian cancer: rates of use and effectiveness, 2018-06-29

• U.S. Food and Drug Administration-Approved Poly (ADP-Ribose) Polymerase Inhibitor Maintenance Therapy for Recurrent Ovarian Cancer: A Cost-Effectiveness Analysis, 2019-03-01

• Laparoscopic Surgical Algorithm to Triage the Timing of Tumor Reductive Surgery in Advanced Ovarian Cancer, 2018-06-23

• Conference Report: Symposium on Advances in Endometrial Cancer Epidemiology and Biology, 2015-07-29

• Toxicity and efficacy of the combination of pembrolizumab with recommended or reduced starting doses of lenvatinib for treatment of recurrent endometrial cancer, 2021-05-03

• Identification of six new susceptibility loci for invasive epithelial ovarian cancer, 2015-01-12

• Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1, 2016-03-29

• Ryanodine receptor 1-mediated Ca2+signaling and mitochondrial reprogramming modulate uterine serous cancer malignant phenotypes, 2022-08-11

• Active Disclosure of Secondary Germline Findings to Deceased Research Participants' Personal Representatives: Process and Outcomes, 2017-10-31

• A multiplexable, microfluidic platform for the rapid quantitation of a biomarker panel for early ovarian cancer detection at the point-of-care, 2014-11-11

• Identification of twelve new susceptibility loci for different histotypes of epithelial ovarian cancer, 2017-03-27

• Novel Approaches to Ovarian Cancer Screening, 2019-07-26

• Factors Prognostic of Survival in Advanced-Stage Uterine Serous Carcinoma, 2017-04-30

• Incidence of Myelodysplastic Syndrome and Acute Myeloid Leukemia in Patients Receiving Poly-ADP Ribose Polymerase Inhibitors for the Treatment of Solid Tumors: A Meta-analysis of Randomized Trials, 2021-03-15

• Salpingectomy as a Means to Reduce Ovarian Cancer Risk, 2015-01-13

• BRCA1andBRCA2Pathogenic Sequence Variants in Women of African Origin or Ancestry, 2019-07-03

• Genotype-Phenotype Correlations by Ethnicity and Mutation Location inBRCAMutation Carriers, 2015-03-19

• High Frequency ofPIK3R1andPIK3R2Mutations in Endometrial Cancer Elucidates a Novel Mechanism for Regulation of PTEN Protein Stability, 2011-07-01

• Clinical Significance of Homologous Recombination Deficiency Score Testing in Endometrial Cancer, 2021-02-06

• A comparison between Lynch syndrome and sporadic colorectal cancer survivors' satisfaction with their healthcare providers, 2017-02-17

• Correction: Hu, W., et al. Targeting Dopamine Receptor D2 by Imipridone Suppresses Uterine Serous Cancer Malignant Phenotype.Cancers2020,12, 2436, 2021-02-04

• Somatic mutation profiles of clear cell endometrial tumors revealed by whole exome and targeted gene sequencing, 2017-05-09

• Evaluation of Clinical Criteria for the Identification of Lynch Syndrome among Unselected Endometrial Cancer Patients, 2014-04-25

• Disparities in treatment and survival among elderly ovarian cancer patients, 2018-09-22

• Targeting Dopamine Receptor D2 by Imipridone Suppresses Uterine Serous Cancer Malignant Phenotype, 2020-08-27

• Women's preferences for cancer risk management strategies in Lynch syndrome, 2018-12-29

• Prospective, Multi-center Randomized Intermediate Biomarker Study of Oral Contraceptive vs. Depo-Provera for Prevention of Endometrial Cancer in Women with Lynch Syndrome, 2013-05-02

• Identification of recurrent focal copy number variations and their putative targeted driver genes in ovarian cancer, 2016-05-26

• INTENSITY-MODULATED RADIOTHERAPY FOR DEFINITIVE TREATMENT OF PARA-AORTIC RELAPSE IN PATIENTS WITH ENDOMETRIAL CANCER, 2012-05-03

• FATS is a transcriptional target of p53 and associated with antitumor activity, 2010-09-16

• Treatment patterns, outcomes, and costs for bowel obstruction in ovarian cancer, 2018-03-12

• Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Promotes Uterine Serous Cancer Cell Proliferation and Cell Cycle Progression, 2020-01-02

• Another Surprise from Metformin: Novel Mechanism of Action via K-Ras Influences Endometrial Cancer Response to Therapy, 2013-09-27

• A prospective phase II study of chemoradiation followed by adjuvant chemotherapy for FIGO stage I-IIIa (1988) uterine papillary serous carcinoma of the endometrium, 2013-02-04

• Modification of Homologous Recombination Deficiency Score Threshold and Association with Long-Term Survival in Epithelial Ovarian Cancer, 2021-02-24

• Predicting high-risk endometrioid carcinomas using proteins, 2018-04-13

• Polygenic risk modeling for prediction of epithelial ovarian cancer risk, 2022-01-14

• Cost-effectiveness of laparoscopic disease assessment in patients with newly diagnosed advanced ovarian cancer, 2021-01-31

• Consequences of Universal MSI/IHC in Screening Endometrial Cancer Patients for Lynch Syndrome, 2014-06-14

• MAGENTA (Making Genetic testing accessible): a prospective randomized controlled trial comparing online genetic education and telephone genetic counseling for hereditary cancer genetic testing, 2019-07-02

• Combined colonoscopy and endometrial biopsy cancer screening results in women with Lynch syndrome, 2014-08-19

• Novel polymer-based system for intrauterine delivery of everolimus for anti-cancer applications, 2021-10-12

• Creation and Implementation of an Environmental Scan to Assess Cancer Genetics Services at Three Oncology Care Settings, 2018-05-16

• No clinical utility ofKRASvariant rs61764370 for ovarian or breast cancer, 2015-05-02

• Immune microenvironment in microsatellite instable endometrial cancers: Hereditary or sporadic origin matters, 2017-03-06

• Health-related quality of life in colorectal cancer survivors: are there differences between sporadic and hereditary patients?, 2018-05-01

• Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer: ASCO Guideline, 2020-01-27

• Endometrial cancer survivors' sleep patterns before and after a physical activity intervention: a retrospective cohort analysis, 2018-02-01

• Identity-related experiences of Asian American trainees in gynecologic oncology, 2022-11-06

• Acceptability of Prophylactic Salpingectomy with Delayed Oophorectomy as Risk-Reducing Surgery Among BRCA Mutation Carriers, 2014-02-28

• ITLN1 modulates invasive potential and metabolic reprogramming of ovarian cancer cells in omental microenvironment, 2020-07-15

• Centers for Medicare and Medicaid Services' Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) scores and gynecologic oncology surgical outcomes, 2019-06-14

• PALB2, CHEK2andATMrare variants and cancer risk: data from COGS, 2016-09-05

• Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration, 2016-07-12

• National trends in bowel and upper abdominal procedures in ovarian cancer surgery, 2020-07-02

• A two stage ovarian cancer screening strategy using the risk of ovarian cancer algorithm (ROCA) identifies early stage incident cancers and demonstrates high positive predictive value, 2013-08-26

• Facilitated cascade testing (FaCT): a randomized controlled trial, 2020-12-18

• Genome-wide Meta-analyses of Breast, Ovarian and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by At Least Two Cancer Types, 2016-07-17

• Mutational Spectrum in a Worldwide Study of 29,700 Families withBRCA1orBRCA2Mutations, 2018-03-12

• Sex hormone regulation of survivin gene expression, 2010-08-26

• ISG15 Promotes ERK1 ISGylation, CD8+ T Cell Activation and Suppresses Ovarian Cancer Progression, 2018-11-22

• Three Lymphadenectomy Strategies in Low-Risk Endometrial Carcinoma: A Cost-Effectiveness Analysis, 2018-04-16

• A Phase II study of oral mammalian target of rapamycin (mTOR) inhibitor, everolimus, in patients with recurrent endometrial carcinoma, 2010-08-02

• Adjuvant Combined-Modality Therapy for Stage IIIC Endometrioid and Non-endometrioid Endometrial Cancer, 2019-05-17

• Stromal Cells Derived from Visceral and Obese Adipose Tissue Promote Growth of Ovarian Cancers, 2015-08-28

• Management of nodal recurrences of endometrial cancer with IMRT, 2015-07-17

• Assessing the genetic architecture of epithelial ovarian cancer histological subtypes, 2016-04-13

• Predictors of optimal cytoreduction in patients with newly diagnosed advanced-stage epithelial ovarian cancer: time to incorporate laparoscopic assessment into the standard of care, 2015-03-28

• Endometrial cancers with activating KRas mutations have activated estrogen signaling and paradoxical response to MEK inhibition, 2017-02-16

• Genome-Wide Association Study inBRCA1Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk, 2013-03-27

• Long-Term Survival Following Definitive Radiation Therapy for Recurrence or Oligometastases in Gynecological Malignancies: A Landmark Analysis, 2021-12-30

• KMT2D/MLL2inactivation is associated with recurrence in adult-type granulosa cell tumors of the ovary, 2018-06-27

• Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer, 2020-04-14

• Cancer spectrum in DNA mismatch repair gene mutation carriers: results from a hospital based Lynch syndrome registry, 2012-06-25

• A universal genetic testing initiative for patients with high-grade, non-mucinous epithelial ovarian cancer and the implications for cancer treatment, 2017-06-10

• Outcomes of Screening Endometrial Cancer Patients for Lynch Syndrome by Patient-Administered Checklist, 2013-10-17

• Energy Balance Related Lifestyle Factors and Risk of Endometrial and Colorectal Cancer among Individuals with Lynch Syndrome: A Systematic Review, 2019-06-24

• Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31, 2013-06-21