Dr. Joseph Bonventre, MD

• Nephrology

• Internal Medicine

*Healthgrades does not verify qualifications for medical specialties. Please verify your provider's specialty and qualifications directly with your provider and applicable medical board.

• Massachusetts General Hospital

  Fellowship Hospital, 1979

• Massachusetts General Hospital

  Residency Hospital, 1978

• Massachusetts General Hospital

  Internship Hospital, 1977

• Harvard Medical School

  Medical School, 1976

• Urine biomarkers of tubular injury do not improve upon the clinical model predicting chronic kidney disease progression, 2016-10-28

• 6ß-Hydroxytestosterone Promotes Angiotensin II-Induced Hypertension via Enhanced Cytosolic Phospholipase A2a Activity, 2021-08-23

• Urinary Biomarkers for Sensitive and Specific Detection of Acute Kidney Injury in Humans, 2009-01-26

• Kidney Injury Molecule-1 Outperforms Traditional Biomarkers of Kidney Injury in Multi-site Preclinical Biomarker Qualification Studies, 2010-05-17

• Urinary KIM-1 is not correlated with gestational age among 5-year-old children born prematurely, 2023-03-20

• Amine-modified single-walled carbon nanotubes protect neurons from injury in a rat stroke model, 2011-01-30

• Human ureteric bud organoids recapitulate branching morphogenesis and differentiate into functional collecting duct cell types, 2022-08-29

• Corrigendum: Immunological Impact of a Gluten-Free Dairy-Free Diet in Children With Kidney Disease: A Feasibility Study, 2021-11-02

• The intensive care medicine agenda on acute kidney injury, 2017-01-30

• Cytosolic Phospholipase A2a and Eicosanoids Regulate Expression of Genes in Macrophages Involved in Host Defense and Inflammation, 2013-07-25

• Comparison of proteomic methods in evaluating biomarker-AKI associations in cardiac surgery patients, 2021-07-31

• Associations of Urinary Levels of Kidney Injury Molecule-1 (KIM-1) and Neutrophil Gelatinase-Associated Lipocalin (NGAL) With Kidney Function Decline in the Multi-Ethnic Study of Atherosclerosis (MESA), 2012-06-30

• Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway, 2012-01-09

• Modeling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids, 2015-10-23

• Tubular damage in chronic systolic heart failure is associated with reduced survival independent of glomerular filtration rate, 2012-08-29

• Associations of Biomarkers of Kidney Tubule Health, Injury, and Inflammation with Left Ventricular Hypertrophy in Children with CKD, 2023-06-12

• Directed Differentiation of Pluripotent Stem Cells to Kidney Cells, 2014-06-13

• ATP/ADP biosensor organoids for drug nephrotoxicity assessment 10.3389/fcell.2023.1138504, 2023-03-02

• CRISPR/Cas9-based Targeted Genome Editing for the Development of Monogenic Diseases Models with Human Pluripotent Stem Cells, 2018-04-26

• Abemaciclib inhibits renal tubular secretion without changing glomerular filtration rate, 2018-12-30

• Associations of Plasma Biomarkers of Inflammation, Fibrosis, and Kidney Tubular Injury With Progression of Diabetic Kidney Disease: A Cohort Study, 2021-11-06

• Mechanism-Based Urinary Biomarkers to Identify the Potential for Aminoglycoside-Induced Nephrotoxicity in Premature Neonates: A Proof-of-Concept Study, 2012-08-24

• Improved clinical trial enrollment criterion to identify patients with diabetes at risk of end stage renal disease, 2017-04-07

• TRIP-Br2 promotes oncogenesis in nude mice and is frequently overexpressed in multiple human tumors, 2009-01-20

• KIM-1 Mediates Fatty Acid Uptake by Renal Tubular Cells to Promote Progressive Diabetic Kidney Disease, 2021-05-04

• Fibroblast growth factor 23 levels are elevated and associated with severe acute kidney injury and death following cardiac surgery, 2016-02-17

• Imperfect Gold Standards for Biomarker Evaluation, 2013-09-03

• Regression of microalbuminuria in type 1 diabetes is associated with lower levels of urinary tubular injury biomarkers, kidney injury molecule-1, andN-acetyl-ß-D-glucosaminidase, 2010-10-27

• Phospholipase A2reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease, 2008-10-19

• Positive effects of a novel non-peptidyl low molecular weight radical scavenger in renal ischemia/reperfusion: a preliminary report, 2014-03-24

• Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias, 2021-03-22

• CYTOSOLIC PHOSPHOLIPASE A2a IS CRITICAL FOR ANGIOTENSIN II - INDUCED HYPERTENSION AND ASSOCIATED CARDIOVASCULAR PATHOPHYSIOLOGY, 2015-02-09

• Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis, 2015-01-05

• Pseudomonas aeruginosaExoU augments neutrophil transepithelial migration, 2017-08-03

• From Bench to the Clinic: The Path to Translation of Nanotechnology-Enabled mRNA SARS-CoV-2 Vaccines, 2022-01-03

• Differences in Immunolocalization of Kim-1, RPA-1, and RPA-2 in Kidneys of Gentamicin-, Cisplatin-, and Valproic Acid-TreatedRats: Potential Role of iNOS and Nitrotyrosine, 2009-06-17

• CD74 deficiency mitigates systemic lupus erythematosus-like autoimmunity and pathological findings in mice, 2017-02-20

• Cyclin G1 and TASCC regulate kidney epithelial cell G2-M arrest and fibrotic maladaptive repair, 2019-01-23

• Increased plasma Kidney Injury Molecule-1 suggests early progressive renal decline in non-proteinuric patients with Type 1 diabetes, 2015-09-15

• Urinary Biomarkers of Kidney Tubule Health and Mortality in Persons with CKD and Diabetes Mellitus, 2023-08-03

• Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury, 2020-07-07

• Circulating kidney injury molecule-1 predicts prognosis and poor outcome in patients with acetaminophen-induced liver injury, 2015-05-29

• Flow-enhanced vascularization and maturation of kidney organoidsin vitro, 2019-02-11

• Prediction of DNA Repair Inhibitor Response in Short Term Patient-Derived Ovarian Cancer Organoids, 2018-09-13

• Nephron organoids derived from human pluripotent stem cells model kidney development and injury, 2015-10-08

• Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis, 2012-03-21

• Reference intervals for urinary renal injury biomarkers KIM-1 and NGAL in healthy children, 2014-03-26

• Absence of long-term changes in urine biomarkers after AKI: findings from the CRIC study, 2022-09-13

• Comparative Analysis of Urinary Biomarkers for Early Detection of Acute Kidney Injury Following Cardiopulmonary Bypass, 2009-06-23

• Water and Sodium in Heart Failure: A Spotlight on Congestion, 2015-04-16

• Nephrotoxicity Assessment with Human Kidney Tubuloids using Spherical Nucleic Acid-Based mRNA Nanoflares, 2021-06-22

• Neutrophil-derived cytosolic PLA2a contributes to bacterial-induced neutrophil trans-epithelial migration, 2017-09-08

• Etiology of P ersistent Micro albuminuria in Nigeria (P_MICRO study): protocol and study design, 2022-07-04

• Kidney Organoids: A Translational Journey, 2017-02-07

• Next-generation biomarkers for detecting kidney toxicity, 2011-01-26

• Concise Reviews: Kidney Generation with Human Pluripotent Stem Cells, 2017-09-26

• SGLT2 Inhibitors and the Risk of Acute Kidney Injury in Older Adults With Type 2 Diabetes, 2021-11-08

• Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids, 2015-10-23

• Evaluation of Putative Renal Cell Carcinoma Markers PAX-2, PAX-8, and hKIM-1 in Germ Cell Tumors: A Tissue Microarray Study of 100 Cases, 2014-05-17

• Differential Roles of Cysteinyl Cathepsins in TGF-ß Signaling and Tissue Fibrosis, 2019-08-09

• Mast cells link immune sensing to antigen-avoidance behaviour, 2023-07-12

• Urinary kidney injury molecule-1 and monocyte chemotactic protein-1 are noninvasive biomarkers of cisplatin-induced nephrotoxicity in lung cancer patients, 2015-09-25

• Recent Advances on Acute Kidney Injury and its Consequences and Impact on Chronic Kidney Disease, 2020-02-04

• Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury, 2010-05-02

• Association of urinary KIM-1, L-FABP, NAG and NGAL with incident end-stage renal disease and mortality in American Indians with type 2 diabetes mellitus, 2014-10-15

• Secreted Factors from Bone Marrow Stromal Cells Upregulate IL-10 and Reverse Acute Kidney Injury, 2012-12-19

• Biomarker validation with an imperfect reference: Issues and bounds, 2017-02-06

• Effect of Renin-Angiotensin-Aldosterone System Inhibition, Dietary Sodium Restriction, and/or Diuretics on Urinary Kidney Injury Molecule 1 Excretion in Nondiabetic Proteinuric Kidney Disease: A Post Hoc Analysis of a Randomized Controlled Trial, 2008-09-27

• Immunological Impact of a Gluten-Free Dairy-Free Diet in Children With Kidney Disease: A Feasibility Study, 2021-06-02

• Biological Variability of Estimated GFR and Albuminuria in CKD, 2018-07-18

• A rapid urine test for early detection of kidney injury, 2009-04-22

• Circulating Kidney Injury Molecule 1 Predicts Prognosis and Poor Outcome in Patients With Acetaminophen-Induced Liver Injury ANTOINE ET AL., 2015-05-29

• Acute kidney injury and chronic kidney disease: from the laboratory to the clinic, 2016-03-10

• KIM-1 as a blood-based marker for early detection of kidney cancer: a prospective nested case-control study., 2018-07-23

• Molecularly Imprinted Polymer Nanogels for Protein Recognition: Direct Proof of Specific Binding Sites by Solution STD and WaterLOGSY NMR Spectroscopies, 2021-08-24

• Haptoglobin or Hemopexin Therapy Prevents Acute Adverse Effects of Resuscitation after Prolonged Storage of Red Cells, 2016-08-11

• Renal Effects of Intensive Volume Removal in Heart Failure Patients with Preexisting Worsening Renal Function, 2019-06-05

• Urinary liver-type fatty acid-binding protein predicts adverse outcomes in acute kidney injury, 2009-11-25

• Plasma Kidney Injury Molecule 1 in CKD: Findings From the Boston Kidney Biopsy Cohort and CRIC Studies, 2021-06-25

• Acute Kidney Injury, 2016-01-14

• Immunohistochemical Distinction of Primary Adrenal Cortical Lesions from Metastatic Clear Cell Renal Cell Carcinoma: A Study of 248 Cases, 2014-05-21

• ADAM17 substrate release in proximal tubule drives kidney fibrosis, 2016-08-18

• Limb Ischemia Protects Against Contrast-Induced Nephropathy, 2012-06-26

• Machine Learning for Acute Kidney Injury Prediction in the Intensive Care Unit, 2022-06-28

• Normalization of urinary biomarkers to creatinine during changes in glomerular filtration rate, 2010-06-16

• Kidney tubules: intertubular, vascular, and glomerular cross-talk, 2016-04-08

• Group IVA phospholipase A2regulates testosterone biosynthesis by murine Leydig cells and is required for timely sexual maturation, 2011-11-01

• Acute Kidney Injury and Progression of Diabetic Kidney Disease, 2018-04-04

• The Prostaglandin E2-EP3 Receptor Axis RegulatesAnaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation, 2016-08-02

• Cytosolic phospholipase A2a protects against ischemia/reperfusion injury in the heart, 2011-05-24

• Uremic solutes and risk of end stage renal disease in type 2 diabetes, 2014-01-15

• Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells, 2016-12-22

• Cystatin C in acute kidney injury diagnosis: early biomarker or alternative to serum creatinine?, 2014-12-05

• Improved performance of urinary biomarkers of acute kidney injury in the critically ill by stratification for injury duration and baseline renal function, 2011-02-09

• A Role for 3D Printing in Kidney-on-a-Chip Platforms, 2016-01-20

• Markers of early progressive renal decline in Type 2 diabetes suggest different implications for etiological studies and prognostic tests development, 2018-02-02

• KIDNEY REPAIR AND REGENERATION: PERSPECTIVES OF THE NIDDK (RE)BUILDING A KIDNEY CONSORTIUM, 2022-03-09

• Clear Cell Papillary Renal Cell Carcinoma and Renal Angiomyoadenomatous Tumor - Two Variants of a Morphologic, Immunohistochemical and Genetic Distinct Entity of Renal Cell Carcinoma, 2015-03-15

• Biomarkers of Kidney Tubule Disease and Risk of End-Stage Kidney Disease in Persons With Diabetes and CKD, 2022-04-05

• High-resolution renal perfusion mapping using contrast-enhanced ultrasound in ischemia-reperfusion injury monitors changes in renal microperfusion, 2016-03-25

• 2-Methoxyestradiol Ameliorates Angiotensin II-Induced Hypertension by Inhibiting Cytosolic Phospholipase A2a Activity in Female Mice, 2021-10-11

• Expression of kidney injury molecule-1 (Kim-1) in relation to necrosis and apoptosis during the early stages of Cd-induced proximal tubule injury, 2009-01-31

• The Aging Kidney: Increased Susceptibility to Nephrotoxicity, 2014-09-01

• cPLA2a-/-sympathetic neurons exhibit increased membrane excitability and loss of N-Type Ca2+current inhibition by M1muscarinic receptor signaling, 2018-12-17

• Can We Target Tubular Damage to Prevent Renal Function Decline in Diabetes?, 2012-10-17

• Tctex-1, a novel interaction partner of Kidney Injury Molecule-1, is required for efferocytosis, 2018-04-25

• Urine Kidney Injury Molecule-1: A Potential Non-invasive Biomarker for Patients with Renal Cell Carcinoma, 2013-08-25

• Pediatric SARS-CoV-2: Clinical Presentation, Infectivity, and Immune Responses, 2020-08-20

• Biomimetic models of the glomerulus, 2022-01-21

• Preclinical Evaluation of Novel Urinary Biomarkers of Cadmium Nephrotoxicity, 2009-02-06

• Acute and long-term disruption of glycometabolic control after SARS-CoV-2 infection, 2021-05-25