Dr. Jeffrey Gershenwald, MD

• General Surgery

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• Cornell University / New York State Statutory Colleges

  Medical School, 1990

• Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma, 2017-04-07

• Inflammatory Marker Testing Identifies CD74 Expression in Melanoma Tumor Cells, and its Expression Associates with Favorable Survival for Stage III Melanoma, 2016-01-18

• Molecular and immunological associations of elevated serum lactate dehydrogenase in metastatic melanoma patients: A fresh look at an old biomarker, 2020-10-05

• Exon capture analysis of G protein-coupled receptors identifies activating mutations inGRM3in melanoma, 2011-09-25

• Clinical activity and safety of combination therapy with temsirolimus and bevacizumab for advanced melanoma: A Phase II trial (CTEP 7190/Mel47), 2013-04-25

• Multi-modal molecular programs regulate melanoma cell state, 2022-07-09

• Chemoprevention Agents for Melanoma: A Path Forward into Phase III Clinical Trials, 2018-10-03

• Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 1st-3rd, 2022-Naples, Italy), 2023-07-28

• Future perspectives in melanoma research: meeting report from the "Melanoma Bridge”, Napoli, December 5th-8th 2013, 2014-10-28

• The association of BMI and outcomes in metastatic melanoma: A retrospective, multicohort analysis of patients treated with targeted therapy, immunotherapy, or chemotherapy, 2018-02-12

• Exome sequencing identifies GRIN2A as frequently mutated in melanoma, 2011-04-15

• Semiconductor-based DNA sequencing of histone modification states, 2013-12-10

• Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy, 2022-06-15

• Beyond BRAFV600: clinical mutation panel testing by next-generation sequencing in advanced melanoma, 2014-08-22

• FUTURE PERSPECTIVES IN MELANOMA RESEARCH. Meeting report from the "Melanoma Research: a bridge from Naples to the World. Napoli, December 5th-6th2011”, 2012-07-04

• Utility of BRAF V600E immunohistochemistry expression pattern as a surrogate ofBRAFmutation status in 154 patients with advanced melanoma, 2015-05-06

• The "Great Debate” at Melanoma Bridge 2021, December 2nd-4th, 2021, 2022-05-10

• The Great Debate at "Melanoma Bridge”, Naples, December 7th, 2019, 2020-04-16

• ErbB3 targeting enhances the effects of MEK inhibitor in wild-type BRAF/NRAS melanoma, 2018-08-16

• Evaluation of Plasma Interleukin-6 in Melanoma Patients as a Prognostic and Checkpoint Immunotherapy Predictive Biomarker, 2021-12-21

• Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response, 2021-12-23

• Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance, 2017-03-01

• The Expression of p-STAT3 in Stage IV Melanoma: Risk of CNS Metastasis and Survival, 2012-04-06

• Prospective Assessment of Lymphedema Incidence and Lymphedema-associated Symptoms Following Lymph Node Surgery for Melanoma, 2013-11-30

• Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set, 2016-10-25

• Neoadjuvant relatlimab and nivolumab in resectable melanoma, 2022-10-26

• Is Surviving Enough? Coping and Impact on Activities of Daily Living Among Melanoma Patients with Lymphoedema, 2015-03-24

• Loss of PTEN promotes resistance to T cell-mediated immunotherapy, 2015-12-08

• Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade, 2016-06-14

• Clinicopathological features and clinical outcomes associated withTP53andBRAFNon-V600mutations in cutaneous melanoma patients, 2016-12-02

• Melanoma Staging: Evidence-Based Changes in the American Joint Committee on Cancer Eighth Edition Cancer Staging Manual, 2017-10-13

• Clinically Significant Risk Thresholds in the Management of Primary Cutaneous Melanoma: A Survey of Melanoma Experts, 2022-05-18

• A Landscape of Driver Mutations in Melanoma, 2012-07-20

• Prognostic Gene Expression Profiling in Cutaneous Melanoma Identifying the Knowledge Gaps and Assessing the Clinical Benefit, 2020-09-01

• Impact of the 2009 (7th Edition) AJCC Melanoma Staging System in the Classification of Thin Cutaneous Melanomas, 2013-12-03

• Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma, 2017-08-14

• Influence of single nucleotide polymorphisms in theMMP1promoter region on cutaneous melanoma progression, 2012-01-12

• The Long-term Risk of Upper-extremity Lymphedema is Two-fold Higher in Breast Cancer Patients than in Melanoma Patients, 2015-10-18

• Biology of Advanced Uveal Melanoma and Next Steps for Clinical Therapeutics, 2014-09-01

• B cells and tertiary lymphoid structures promote immunotherapy response, 2020-01-15

• A highly recurrent RPS27 5'UTR mutation in melanoma, 2014-06-01

• Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases, 2019-02-20

• FOXD3 Regulates VISTA Expression in Melanoma, 2020-01-14

• Role of ElevatedPHIPCopy Number as a Prognostic and Progression Marker for Cutaneous Melanoma, 2018-05-18

• The "Great Debate” at Melanoma Bridge 2020: December, 5th, 2020, 2021-04-07

• The Great Debate at "Melanoma Bridge”, Napoli, December 2nd, 2017, 2018-04-17

• Complete loss of PTEN protein expression correlates with shorter time to brain metastasis and survival in stage IIIB/C melanoma patients with BRAFV600mutations, 2014-08-27

• The eighth edition American Joint Committee on Cancer (AJCC) melanoma staging system: implications for melanoma treatment and care, 2020-11-02

• Sex Differences in Age at Primary Melanoma Diagnosis in a Population-Based Analysis (US Surveillance, Epidemiology, and End Results, 2005-2011), 2016-05-29

• Somatic mutations in MAP3K5 attenuate its pro-apoptotic function in melanoma through increased binding to Thioredoxin, 2013-09-05

• Correlates of Sun Protection and Sunburn in Children of Melanoma Survivors, 2016-04-07

• 4-Nitroquinoline-1-oxide-induced mutagen sensitivity and risk of cutaneous melanoma: a case-control analysis, 2016-07-12

• Hypo Adenosine-to-Inosine miR-455-5p Editing Promotes Melanoma Growth and Metastasis, 2015-02-16

• Author Correction: Neoadjuvant relatlimab and nivolumab in resectable melanoma, 2023-03-09

• Specific lymphocyte subsets predict response to adoptive cell therapy using expanded autologous tumor-infiltrating lymphocytes in metastatic melanoma patients, 2012-10-02

• Melanoma expression genes identified through genome-wide association study of Breslow tumor thickness, 2016-08-06

• The relationship between blood IL-12p40 level and melanoma progression, 2014-09-18

• Role of immune response, inflammation and tumor immune response-related cytokines/chemokines in melanoma progression, 2019-06-07

• Assessment of Compliance with Texas Legislation Banning Indoor UV Tanning by Minors, 2017-02-01

• Presence of Circulating Tumor Cells Predates Imaging Detection of Relapse in Patients with Stage III Melanoma, 2023-07-15

• Clinical impact of ulceration width, lymphovascular invasion, microscopic satellitosis, perineural invasion, and mitotic rate in patients undergoing sentinel lymph node biopsy for cutaneous melanoma: a retrospective observational study at a comprehensive cancer center, 2018-02-21

• Biological Validation of RNA Sequencing Data from Formalin-Fixed Paraffin-Embedded Primary Melanomas, 2018-06-14

• The "Great Debate” at Melanoma Bridge 2022, Naples, December 1st-3rd, 2022, 2023-04-18

• Nodal recurrence is a primary driver of early relapse for patients with sentinel lymph node positive melanoma in the modern therapeutic era, 2021-04-15

• State of the Science on Prevention and Screening to Reduce Melanoma Incidence and Mortality: The Time is Now, 2016-05-27

• AMERICAN JOINT COMMITTEE ON CANCER ACCEPTANCE CRITERIA FOR INCLUSION OF RISK MODELS FOR INDIVIDUALIZED PROGNOSIS IN THE PRACTICE OF PRECISION MEDICINE, 2016-01-19

• Identification of MicroRNA-mRNA Networks in Melanoma and Their Association with PD-1 Checkpoint Blockade Outcomes, 2021-10-22

• The State of Melanoma: Emergent Challenges and Opportunities, 2021-01-07