Dr. James Welsh, MD

• Radiation Oncology

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• Dartmouth College

  Medical School, 2003

• Circulating MicroRNAs as Noninvasive Biomarkers in Breast Cancer, 2013-11-21

• A radioenhancing nanoparticle mediated immunoradiation improves survival and generates long-term antitumor immune memory in an anti-PD1-resistant murine lung cancer model, 2021-12-11

• NBTXR3 improves the efficacy of immunoradiotherapy combining nonfucosylated anti-CTLA4 in an anti-PD1 resistant lung cancer model, 2022-11-03

• Comparative Effectiveness of Five Treatment Strategies for Early-Stage Non-Small Cell Lung Cancer in the Elderly, 2012-09-11

• Stereotactic Ablative Radiotherapy is a Highly Effective Treatment for Early Stage Non-Small Cell Lung Cancer in Elderly Patients, 2016-12-21

• Bone morphogenetic protein 7 promotes resistance to immunotherapy, 2020-09-24

• Metastasis is regulated via microRNA-200/ZEB1 axis control of tumor cell PD-L1 expression and intratumoral immunosuppression, 2014-10-28

• Progress in the Management of Limited-Stage Small Cell Lung Cancer, 2013-12-10

• Pulsed Radiation Therapy to Improve Systemic Control of Metastatic Cancer, 2021-08-23

• Radiation followed by OX40 stimulation drives local and abscopal antitumor effects in an anti-PD1-resistant lung tumor model, 2018-05-21

• NLRP3 agonist enhances radiation-induced immune priming and promotes abscopal responses in anti-PD1 resistant model, 2023-02-13

• Aortic Dose Constraints when Reirradiating Thoracic Tumors, 2013-02-28

• Phase II Trial of Ipilimumab with Stereotactic Radiation Therapy for Metastatic Disease: Outcomes, Toxicities, and Low-Dose Radiation-Related Abscopal Responses, 2019-10-28

• Suppression of type I IFN signaling in tumors mediates resistance to anti-PD-1 treatment that can be overcome by radiotherapy, 2016-11-07

• Nanoparticle-enhanced proton beam immunoradiotherapy drives immune activation and durable tumor rejection, 2023-06-22

• A Prospective Exploratory Analysis of Cardiac Biomarkers and Electrocardiogram Abnormalities in Patients Receiving Thoracic Radiation Therapy with High-Dose Heart Exposure, 2014-06-22

• NLRP3 agonist enhances radiation-induced immune priming and promotes abscopal responses in anti-PD1 resistant model, 2023-06-08

• An Analysis of Factors Affecting Successful Clinical Trial Enrollment in the Context of Three Prospective Randomized Control Trials, 2016-11-27

• High Plus Low Dose Radiation Strategy in Combination with TIGIT and PD1 Blockade to Promote Systemic Antitumor Responses, 2022-01-03

• The potential of biology-guided radiation therapy in thoracic cancer: A preliminary treatment planning study, 2022-10-14

• Stereotactic Ablative Radiotherapy: A Potentially Curable Approach to Early-Stage Multiple Primary Lung Cancer, 2013-06-24

• Strategies for combining immunotherapy with radiation for anticancer therapy, 2015-08-27

• Predicting 5-Year Progression and Survival Outcomes for Early-Stage Non-Small Cell Lung Cancer Treated with Stereotactic Ablative Radiotherapy: Development and Validation of Robust Prognostic Nomograms, 2019-10-03

• Association of Long-term Outcomes and Survival With Multidisciplinary Salvage Treatment for Local and Regional Recurrence After Stereotactic Ablative Radiotherapy for Early-Stage Lung Cancer Outcomes With Salvage Treatment for Recurrence After Radiotherapy for Lung Cancer, 2018-08-24

• Stereotactic Ablative Radiation Therapy Combined With Immunotherapy for Solid Tumors, 2017-11-02

• Safety and Efficacy of Stereotactic Body Radiation Therapy for Locoregional Recurrences After Prior Chemoradiation for Advanced Esophageal Carcinoma, 2020-07-31

• Combining a nanoparticle-mediated immunoradiotherapy with dual blockade of LAG3 and TIGIT improves the treatment efficacy in anti-PD1 resistant lung cancer, 2022-09-19

• Role of Mitochondria in Cancer Immune Evasion and Potential Therapeutic Approaches, 2020-10-16

• Prognostic Significance of Pretreatment Total Lymphocyte Count and Neutrophil-to-Lymphocyte Ratio in Extensive-Stage Small-Cell Lung Cancer, 2018-02-02

• Radiation-induced lymphopenia during chemoradiation therapy for non-small cell lung cancer is linked with age, lung V5, and XRCC1 rs25487 genotype in lymphocytes, 2020-09-09

• Adding Erlotinib to Chemoradiation Improves Overall Survival but not Progression-Free Survival in Stage III Non-Small-Cell Lung Cancer, 2015-06-01

• Indoleamine 2,3-dioxygenase 1 inhibition targets anti-PD1-resistant lung tumors by blocking myeloid-derived suppressor cells, 2018-05-08

• Development of an Immune-Pathology Informed Radiomics Model for Non-Small Cell Lung Cancer, 2018-01-31

• Role of Radiation Therapy in Modulation of the Tumor Stroma and Microenvironment, 2019-02-15

• A mathematical model for the quantification of a patient's sensitivity to checkpoint inhibitors and long-term tumour burden, 2021-01-04

• Anti-glucocorticoid-induced Tumor Necrosis Factor-Related Protein (GITR) Therapy Overcomes Radiation-Induced Treg Immunosuppression and Drives Abscopal Effects, 2018-09-20

• Author Correction: Bone morphogenetic protein 7 promotes resistance to immunotherapy, 2020-10-08

• Triple Therapy with MerTK and PD1 Inhibition plus Radiotherapy Promotes Abscopal Antitumor Immune Responses, 2019-09-20

• Pulsed radiotherapy to mitigate high tumor burden and generate immune memory, 2022-10-06

• Ipilimumab with stereotactic ablative radiation therapy: Phase I results and immunologic correlates from peripheral T-cells, 2016-09-20

• Outcomes and toxicities following stereotactic ablative radiotherapy for pulmonary metastases in patients with primary head and neck cancer, 2020-03-04

• Modulation of c-Met signaling and cellular sensitivity to radiation: potential implications for therapy, 2013-02-19

• The role of tumor metabolism in modulating T-Cell activity and in optimizing immunotherapy, 2023-04-26

• Outcomes of re-irradiation for brain recurrence after prophylactic or therapeutic whole-brain irradiation for small cell lung Cancer: a retrospective analysis, 2018-12-29

• Association of Medicaid Insurance With Survival Among Patients With Small Cell Lung Cancer Association of Medicaid Insurance With Survival Among Patients With Small Cell Lung Cancer, 2020-04-22

• Inhibition of STAT6 with Antisense Oligonucleotides Enhances the Systemic Antitumor Effects of Radiotherapy and Anti-PD1 in Metastatic Non-Small Cell Lung Cancer, 2023-04-03

• Stereotactic Ablative Radiotherapy for Operable Stage I Non-Small Cell Lung Cancer: Long-Term Results of the Single-Arm STARS Prospective Trial, 2021-09-13

• Incidence of Second Malignancy after Successful Treatment of Limited-Stage Small-Cell Lung Cancer and Its Effects on Survival, 2017-08-10

• Radiation and Anti-Cancer Vaccines: A Winning Combination, 2018-01-30

• Combining Radiation and Immunotherapy: A New Systemic Therapy for Solid tumors?, 2017-02-15

• Modeling the impact of cardio-pulmonary irradiation on overall survival in NRG Oncology trial RTOG 0617, 2020-05-12

• Novel Use of Low-Dose Radiotherapy to Modulate the Tumor Microenvironment of Liver Metastases, 2021-12-15