Dr. Genevieve Boland, MD

• Surgical Oncology

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• Thomas Jefferson University

  Medical School, 2006

• Prediction of early-stage melanoma recurrence using clinical and histopathologic features, 2022-10-31

• Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence, 2017-12-05

• Primary Vascular Leiomyosarcoma: Clinical Observations and Molecular Variables, 2016-04-01

• A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade, 2018-11-01

• Neural crest-like stem cell transcriptome analysis identifies LPAR1 in melanoma progression and therapy resistance., 2021-08-30

• Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy, 2020-06-29

• CRISPR Screens Identify Essential Cell Growth Mediators in BRAF Inhibitor-resistant Melanoma, 2020-05-13

• Pathway signatures derived from on-treatment tumor specimens predict response to anti-PD1 blockade in metastatic melanoma, 2021-10-15

• Induction of Telomere Dysfunction Prolongs Disease Control of Therapy-Resistant Melanoma, 2018-03-21

• Targeting TBK1 to overcome resistance to cancer immunotherapy, 2023-01-12

• The lipogenic regulatorSREBF2inducesTransferrinin circulating melanoma cells and suppresses ferroptosis, 2020-11-17

• Effect of Cancer Stage on Adverse Kidney Outcomes in Patients Receiving Immune Checkpoint Inhibitors for Melanoma, 2022-09-08

• Clinical next generation sequencing to identify actionable aberrations in a phase I program, 2015-05-08

• A fatty acid oxidation-dependent metabolic shift regulates the adaptation ofBRAF-mutated melanoma to MAPK inhibitors, 2019-08-02

• Reversal of pre-existing NGFR-driven tumor and immune therapy resistance, 2020-08-07

• Activation of PI3K signaling in Merkel cell carcinoma, 2012-01-18

• Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps, 2021-12-14

• HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8+T-cell infiltration into tumors, 2022-07-14

• CDK4/6 Inhibition Augments Anti-Tumor Immunity by Enhancing T Cell Activation, 2017-11-03

• Downregulation of KEAP1 in melanoma promotes resistance to immune checkpoint blockade, 2023-03-02

• STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming, 2022-04-06

• Mixed Response to Immunotherapy in Patients with Metastatic Melanoma, 2020-05-29

• Resistance to checkpoint blockade therapy through inactivation of antigen presentation, 2017-10-26

• Low expression of the PPAR?-regulated gene thioredoxin-interacting protein accompanies human melanoma progression and promotes experimental lung metastases, 2021-04-12

• Fucosylation of HLA-DRB1 regulates CD4+T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy, 2023-01-23

• Evolution of Delayed Resistance to Immunotherapy in a Melanoma Responder, 2021-05-03

• Minimal Residual Disease Detection using a Plasma-Only Circulating Tumor DNA Assay in Colorectal Cancer Patients, 2021-04-29

• Defining T cell states associated with response to checkpoint immunotherapy in melanoma, 2018-11-01

• The human and mouse enteric nervous system at single cell resolution, 2020-09-03

• PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hicells and anti-PD-1 resistance, 2019-07-29

• Spatially organized multicellular immune hubs in human colorectal cancer, 2021-08-26

• Intratumoral activity of the CXCR3 chemokine system is required for the efficacy of anti- PD-1 therapy, 2019-05-13

• Plasma glycoproteomic biomarkers identify metastatic melanoma patients with reduced clinical benefit from immune checkpoint inhibitor therapy, 2023-06-14

• Author Correction: Reversal of pre-existing NGFR-driven tumor and immune therapy resistance, 2023-02-07

• PAK Signaling Drives Acquired Drug Resistance to MAPK Inhibitors inBRAF-mutant Melanomas, 2017-09-27

• Immune Responses in Checkpoint Myocarditis Across Heart, Blood, and Tumor, 2023-09-18

• Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling, 2020-08-12

• Epitope spreading toward wild type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses, 2021-02-17

• Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma, 2021-07-21

• Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells, 2017-03-06

• Stressed target cancer cells drive nongenetic reprogramming of CAR T cells and solid tumor microenvironment, 2023-09-15

• Landscape of helper and regulatory antitumor CD4+T cells in melanoma, 2022-05-04

• Ex VivoProfiling of PD-1 Blockade Using Organotypic Tumor Spheroids, 2017-11-03

• Lineage Tracing In Humans Enabled By Mitochondrial Mutations And Single Cell Genomics, 2019-02-28

• Microenvironmental landscape of human melanoma brain metastases in response to immune checkpoint inhibition, 2022-08-03