Dr. Eva Feldman, MD

• Neurology

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• University Of Michigan / Ann Arbor

  Medical School, 1983

• Kindlin-2 is required for myocyte elongation and is essential for myogenesis, 2008-07-08

• Genome-wide Analyses Identify KIF5A as a Novel ALS Gene, 2018-03-21

• Towards prevention of diabetic peripheral neuropathy: clinical presentation, pathogenesis, and new treatments, 2023-04-06

• Associations of self-reported occupational exposures and settings to ALS: a case-control study, 2022-05-20

• Peripheral neuropathy: the importance of rare subtypes, 2016-10-15

• Systems Biology to Address Unmet Medical Needs in Neurological Disorders, 2022-08-31

• The metabolic drivers of neuropathy in India, 2020-06-11

• Dietary weight loss in the severely obese stabilizes neuropathy and improves symptomatology, 2021-11-07

• Peripheral nervous system insulin resistance inob/obmice, 2013-05-10

• 25 years of neuroimaging in amyotrophic lateral sclerosis, 2013-08-06

• Stem cell treatments for amyotrophic lateral sclerosis (ALS): A critical overview of early phase trials, 2019-06-12

• Enhanced glucose control for preventing and treating diabetic neuropathy, 2012-06-13

• Decreased glycolytic and tricarboxylic acid cycle intermediates coincide with peripheral nervous system oxidative stress in a murine model of type 2 diabetes, 2013-01-02

• Modeling the innate inflammatory cGAS/STING pathway: sexually dimorphic effects on microglia and cognition in obesity and prediabetes, 2023-05-03

• Effect of Mild Hyperglycemia on Autonomic Function in Obstructive Sleep Apnea, 2011-07-28

• Diabetic neuropathy, 2019-06-13

• The Role of Oxidized Cholesterol in Diabetes-induced Lysosomal Dysfunction in the Brain, 2015-05-15

• Effects of Exenatide on Measures of Diabetic Neuropathy in Subjects with Type 2 Diabetes: Results from an 18-Month Proof-of-Concept Open Label Randomized Study, 2015-07-17

• The Role of Environmental Toxins on ALS: A Case-Control Study of Occupational Risk Factors, 2016-07-01

• Transcriptional networks of progressive diabetic peripheral neuropathy in thedb/dbmouse model of type 2 diabetes: an inflammatory story, 2018-03-14

• Comparative RNA-Seq transcriptome analyses reveal distinct metabolic pathways in diabetic nerve and kidney disease, 2017-03-08

• Electrodiagnostic tests in polyneuropathy and radiculopathy, 2016-01-19

• Cytoplasmic TDP43 Binds microRNAs: New Disease Targets in Amyotrophic Lateral Sclerosis, 2020-05-12

• Ontology-basedBrucellavaccine literature indexing and systematic analysis of gene-vaccine association network, 2011-08-26

• Computational methods for identifying a layered allosteric regulatory mechanism for ALS-causing mutations of Cu-Zn superoxide dismutase 1, 2010-10-22

• Extracellular Vesicles in Serum and Central Nervous System Tissues Contain microRNA Signatures in Sporadic Amyotrophic Lateral Sclerosis, 2021-10-29

• Computational Methods for Predicting Sites of Functionally Important Dynamics, 2009-05-14

• Bioenergetics in Diabetic Neuropathy- What We Need to Know, 2013-02-26

• Monoclonal antibody-mediated immunosuppression enables long-term survival of transplanted human neural stem cells in mouse brain, 2022-09-13

• Gut microbiota in a mouse model of obesity and peripheral neuropathy associated with plasma and nerve lipidomics and nerve transcriptomics, 2023-03-15

• High plasma concentrations of organic pollutants negatively impact survival in amyotrophic lateral sclerosis, 2019-02-13

• Identification of Epigenetically Altered Genes in Sporadic Amyotrophic Lateral Sclerosis, 2012-12-26

• Electrodiagnostic tests are unlikely to change management in those with a known cause of typical distal symmetric polyneuropathy, 2017-06-22

• New Horizons in Diabetic Neuropathy: Mechanisms, Bioenergetics, and Pain, 2017-03-22

• Better diagnostic accuracy of neuropathy in obesity: A new challenge for neurologists, 2018-01-16

• Temporal evolution of the microbiome, immune system and epigenome with disease progression in ALS mice, 2019-11-15

• Hydrogen Peroxide-Induced Akt Phosphorylation Regulates Bax Activation, 2009-02-06

• Energizing the Conversation: How to Identify and Overcome Gender Inequalities in Academic Medicine, 2021-07-29

• Voicing the need for ALS environmental research, 2020-05-01

• The role of endoplasmic reticulum stress in hippocampal insulin resistance, 2016-01-13

• Stem cell therapies for amyotrophic lateral sclerosis: Recent advances and prospects for the future, 2014-10-17

• Association between brain health outcomes and metabolic risk factors in persons with diabetes E. L. Reynoldset al., 2023-07-30

• The Role of Oxidative Stress in Nervous System Aging, 2013-07-02

• Hyperlipidemia: A New Therapeutic Target for Diabetic Neuropathy, 2014-11-14

• ALS: one size does not fit all, 2017-04-21

• Disorders of Cranial Nerves IX and X, 2009-02-12

• Dietary reversal of neuropathy in a murine model of prediabetes and metabolic syndrome, 2017-06-01

• The determinants of complication trajectories in American Indians with type 2 diabetes, 2021-05-24

• Neuromuscular effects of G93A-SOD1 expression in zebrafish, 2012-08-31

• Conserved Transcriptional Signatures in Human and Murine Diabetic Peripheral Neuropathy, 2018-12-05

• Transcriptomic analysis of diabetic kidney disease and neuropathy in mouse models of type 1 and type 2 diabetes, 2023-10-04

• Mitochondrial uncoupling has no effect on microvascular complications in type 2 diabetes, 2019-01-29

• Reliability of Quantitative Sudomotor Axon Reflex Testing and Quantitative Sensory Testing in Neuropathy of Impaired Glucose Regulation, 2015-04-01

• Emerging insights into the complex genetics and pathophysiology of ALS, 2022-03-22

• Vascular endothelial growth factor prevents G93A-SOD1-induced motor neuron degeneration, 2010-03-23

• Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy, 2020-08-12

• Dual CCR2/CCR5 antagonist treatment attenuates adipose inflammation, but not microvascular complications inob/obmice, 2017-06-02

• Central obesity is associated with neuropathy in the severely obese, 2020-04-29

• INTERPLAY BETWEEN IMMUNITY AND AMYOTROPHIC LATERAL SCLEROSIS: CLINICAL IMPACT, 2021-06-19

• Recent advances in the diagnosis and prognosis of ALS, 2022-03-22

• BTBRob/obmice as a novel diabetic neuropathy model: neurological characterization and gene expression analyses, 2014-10-30

• Diabetic Neuropathy: One disease or two?, 2014-11-14

• Amyotrophic lateral sclerosis, 2022-09-15

• DEFINING DISABILITY: DEVELOPMENT AND VALIDATION OF A DISABILITY SEVERITY INDEX IN INHERITED NEUROPATHY, 2014-08-25

• Dysregulated biodynamics in metabolic attractor systems precede the emergence of amyotrophic lateral sclerosis, 2020-04-15

• Transcriptional networks of murine diabetic peripheral neuropathy and nephropathy: common and distinct gene expression patterns, 2016-03-21

• Diffusion tensor imaging of the sural nerve in normal controls, 2014-04-28

• Diagnostic and Therapeutic Advances: Distal Symmetric Polyneuropathy, 2015-11-24

• Environmental Risk Factors and Amyotrophic Lateral Sclerosis (ALS): A Case-Control Study of ALS in Michigan, 2014-06-30

• How to Choose (even more) Wisely: Prioritizing waste reduction targets and identifying gaps in knowledge, 2014-04-23

• Two Dynamin-2 Genes Are Required for Normal Zebrafish Development, 2013-02-13

• Expression of MicroRNAs in Human Post-mortem Amyotrophic Lateral Sclerosis Spinal Cords Provides Insight into Disease Mechanisms, 2015-12-17

• Neuropsychological Outcomes in Individuals With Type 1 and Type 2 Diabetes, 2022-03-04

• Human neural stem cell transplantation improves cognition in a murine model of Alzheimer's disease, 2018-10-03

• Differential Effects of Empagliflozin on Microvascular Complications in Murine Models of Type 1 and Type 2 Diabetes, 2020-10-22

• Neurodegeneration and early lethality in SOD2-deficient mice: a comprehensive analysis of the central and peripheral nervous systems, 2012-04-16

• Dietary Reversal Ameliorates Short- and Long-Term Memory Deficits Induced by High-fat Diet Early in Life, 2016-09-27

• Mitochondrial Biogenesis and Fission in Axons in Cell Culture and Animal Models of Diabetic Neuropathy, 2010-05-15

• Intraspinal Stem Cell Transplantation for Amyotrophic Lateral Sclerosis, 2016-02-12

• Exploring the association between metabolic syndrome components and polyneuropathy in an obese population, 2016-12-01

• Inflammation as a Therapeutic Target for Diabetic Neuropathies, 2016-10-22

• ALS/SURV: A modification of the CAFS statistic, 2019-07-23

• Diabetic neuropathy: what does the future hold?, 2020-01-23

• Mediators of diabetic neuropathy - is hyperglycemia the only culprit?, 2018-02-15

• Intraspinal Neural Stem Cell Transplantation in ALS Subjects: Phase I Trial Outcomes, 2014-03-07

• Diabetic neuropathy: Clinical manifestations and current treatments, 2012-05-16

• Obesity-induced neuroinflammation and cognitive impairment in young adult versus middle-aged mice, 2022-12-22

• Neurological Consequences of Obesity, 2017-06-01

• Correction to: Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy, 2020-08-27

• Design-Based Stereology and Binary Image Histomorphometry in Nerve Assessment, 2020-02-15

• The role of neurologists and diagnostic tests in the management of distal symmetric polyneuropathy, 2014-11-20

• Differential effects of minocycline on microvascular complications in murine models of type 1 and type 2 diabetes, 2020-06-16

• Cardiovascular Autonomic Neuropathy in Adolescents and Young Adults with Type 1 and Type 2 Diabetes: The SEARCH for Diabetes in Youth Cohort Study, 2018-01-02

• Literature-based discovery of diabetes- and ROS-related targets, 2010-10-27

• Differential Impact of Type-1 and Type-2 Diabetes on Control of Heart Rate in Mice, 2015-12-17

• New insights into the mechanisms of diabetic complications: role of lipids and lipid metabolism, 2019-07-25

• Gender-specific differences in diabetic neuropathy in BTBRob/obmice, 2015-10-03

• Effects of Prior Intensive Insulin Therapy on Cardiac Autonomic Nervous System Function in Type 1 Diabetes: The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study (DCCT/EDIC), 2009-05-26

• cGAS/STING and innate brain inflammation following acute high-fat feeding, 2022-09-29

• A novel approach to study motor neurons from zebrafish embryos and larvae in culture, 2012-01-20

• Glial-neuron crosstalk in health and disease: A focus on metabolism, obesity, and cognitive impairment, 2022-05-16

• Sex differences in insulin resistance, but not peripheral neuropathy, in a diet-induced prediabetes mouse model, 2021-04-15

• Integrated lipidomic and transcriptomic analyses identify altered nerve triglycerides in mouse models of prediabetes and type 2 diabetes, 2020-01-24

• 3T MR Spectroscopy Reveals an Imbalance between Excitatory and Inhibitory Neurotransmitters in Amyotrophic Lateral Sclerosis, 2015-03-13