Dr. Edwin Posadas, MD

• Hematology

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• Johns Hopkins School Of Medicine

  Medical School, 1997

• English

• Filipino

• French

• Italian

• Tagalog

• Thai

• A phase 2 study of KX2-391, an oral inhibitor of Src kinase and tubulin polymerization, in men with bone-metastatic castration-resistant prostate cancer, 2013-01-13

• Circulating Fatty Objects and Their Preferential Presence in Pancreatic Cancer Patient Blood Samples, 2022-02-14

• Prostate cancer extracellular vesicle digital scoring assay - a rapid noninvasive approach for quantification of disease-relevant mRNAs, 2023-01-03

• Sub-classification of prostate cancer circulating tumor cells (CTCs) by nuclear size reveals very-small nuclear CTCs in patients with visceral metastases, 2015-05-14

• Discovery and characterization of circulating tumor cell clusters in neuroendocrine tumor patients using nanosubstrate-embedded microchips, 2021-12-03

• Quantitative and Qualitative Analysis of Blood-based Liquid Biopsies to Inform Clinical Decision-making in Prostate Cancer, 2021-01-07

• S-adenosylmethionine and methylthioadenosine inhibit cancer metastasis by targeting microRNA 34a/b-methionine adenosyltransferase 2A/2B axis, 2017-08-12

• Future perspectives of prostate cancer therapy, 2012-01-03

• A comparison of isolated circulating tumor cells and tissue biopsies using whole-genome sequencing in prostate cancer, 2015-11-05

• Receptor-interacting protein kinase 2 (RIPK2) stabilizes c-Myc and is a therapeutic target in prostate cancer metastasis, 2022-02-03

• miR-409-3p/-5p promotes tumorigenesis, epithelial to mesenchymal transition and bone metastasis of human prostate cancer, 2014-06-24

• SRC family kinase FYN promotes the neuroendocrine phenotype and visceral metastasis in advanced prostate cancer, 2015-11-26

• NanoVelcro Chip for CTC enumeration in prostate cancer patients, 2013-06-29

• Saracatinib as a Metastasis Inhibitor in Metastatic Castration-Resistant Prostate Cancer: A University of Chicago Phase 2 Consortium and DOD/PCF Prostate Cancer Clinical Trials Consortium Study, 2015-10-23

• miR-154* and miR-379 in the DLK1-DIO3 microRNA mega-cluster regulate epithelial to mesenchymal transition and bone metastasis of prostate cancer, 2014-10-16

• NanoVelcro Rare-Cell Assays for Detection and Characterization of Circulating Tumor Cells, 2018-03-15

• A cisplatin conjugate with tumor cell specificity exhibits antitumor effects in renal cancer models, 2023-06-02

• Phase 2 Trial of Linifanib (ABT-869) in Patients with Advanced Renal Cell Cancer (RCC) after Sunitinib Failure, 2011-11-10

• High-Purity Prostate Circulating Tumor Cell Isolation by a Polymer Nanofiber-Embedded Microchip for Whole Exome Sequencing, 2013-03-26

• Glycan Stimulation Enables Purification of Prostate Cancer Circulating Tumor Cells on PEDOT NanoVelcro Chips for RNA Biomarker Detection, 2017-09-11

• HCC EV ECG score: An extracellular vesicle-based protein assay for detection of early-stage hepatocellular carcinoma, 2023-02-17

• A randomized phase II study of pazopanib in hormone sensitive prostate cancer: a University of Chicago Phase II Consortium/ Department of Defense Prostate Cancer Clinical Trials Consortium study, 2011-10-18

• Detection of Live Circulating Tumor Cells by a Class of Near-Infrared Heptamethine Carbocyanine Dyes in Patients with Localized and Metastatic Prostate Cancer, 2014-02-14

• Covalent Chemistry-Mediated Multimarker Purification of Circulating Tumor Cells Enables Noninvasive Detection of Molecular Signatures of Hepatocellular Carcinoma, 2021-04-09

• Fyn is downstream of the HGF/MET signaling axis and affects cellular shape and tropism in PC3 cells, 2011-03-01

• Loss of testosterone impairs anti-tumor neutrophil function, 2020-03-31

• Modulation of cabozantinib efficacy by the prostate tumor microenvironment, 2017-09-23

• Randomized phase II trial of sipuleucel-T with or without radium-223 in men with bone-metastatic castration-resistant prostate cancer, 2021-01-15

• The 5-Hydroxymethylcytosine Landscape of Prostate Cancer, 2022-10-17

• Circulating monocytes from prostate cancer patients promote invasion and motility of epithelial cells, 2018-08-09

• A comparative study of PCS and PAM50 prostate cancer classification schemes, 2021-02-02