Dr. Douglas Kiel, MD

• Internal Medicine

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• University Of California At Berkeley

  Medical School, 1995

• Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis EPIGENETICS, 2023-05-26

• Facility and State Variation in Hip Fracture among US Nursing Home Residents, 2018-01-16

• Discontinuation of Beta Blockers among Nursing Home Residents at End of Life, 2021-10-20

• Association Between Bisphosphonates and HospitalizedClostridioides difficileInfection Among Frail Older Adults, 2020-01-10

• Bone density and strength from thoracic and lumbar CT scans both predict incident vertebral fractures independently of fracture location, 2020-08-03

• Parent-of-origin specific allelic associations among 106 genomic loci for age at menarche, 2014-07-23

• Diuretic Initiation and the Acute Risk of Hip Fracture, 2012-07-13

• Whole-genome sequencing identifiesEN1as a determinant of bone density and fracture, 2015-09-14

• Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: a large Mendelian randomisation study, 2018-08-14

• An atlas of genetic influences on osteoporosis in humans and mice, 2018-12-31

• Heritability and Genetic Correlations for Bone Microarchitecture: The Framingham Study Families, 2016-10-26

• Effect of Bisphosphonates on Fracture Outcomes among Frail Older Adults, 2018-12-21

• Association of total protein intake with bone mineral density (BMD) and bone loss in men and women from the Framingham Offspring Study, 2013-10-29

• Genetic diversity is a predictor of mortality in humans, 2014-12-29

• Metabolomics insights into osteoporosis through association with bone mineral density, 2021-02-02

• A Longitudinal Study of Disc Height Narrowing and Facet Joint Osteoarthritis at The Thoracic and Lumbar Spine, Evaluated by Computed Tomography: The Framingham Study, 2018-04-19

• Defining terms commonly used in sarcopenia research: a glossary proposed by the Global Leadership in Sarcopenia (GLIS) Steering Committee, 2022-11-29

• Atrial fibrillation and the risk of subsequent fracture, 2020-03-05

• Association between Inflammatory Biomarkers and Bone Mineral Density in a Community-based Cohort of Men and Women: The Framingham Osteoporosis Study, 2014-02-03

• Epigenetic Signatures of Cigarette Smoking, 2016-09-20

• Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels, 2018-01-17

• Preventing Hip Fractures in Older Adults in 2019, 2019-06-11

• A combined reference panel from the 1000 Genomes and UK10K projects improved rare variant imputation in European and Chinese samples, 2016-12-22

• The Musculoskeletal Knowledge Portal: improving access to multi-omics data, 2022-07-29

• New loop diuretic prescriptions may be an acute risk factor for falls in the nursing home, 2012-03-16

• In silico discovery of blood cell macromolecular associations, 2022-07-26

• The Factor-of-Risk Biomechanical Approach Predicts Hip Fracture In Men and Women: The Framingham Study, 2011-02-23

• Large meta-analysis of genome-wide association studies identifies five loci for lean body mass, 2017-07-19

• Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women, 2021-01-28

• Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness, 2017-07-12

• New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk, 2016-02-01

• Low Magnitude Mechanical Stimulation to Improve Bone Density in Persons of Advanced Age: A Randomized, Placebo-Controlled Trial, 2016-04-13

• The complex genetics of gait speed: genome-wide meta-analysis approach, 2017-01-10

• The Ability of Low Magnitude Mechanical Signals to Normalize Bone Turnover in Adolescents Hospitalized for Anorexia Nervosa, 2016-12-01

• Predictors of Hip Fracture despite Treatment with Bisphosphonates among Frail Older Adults, 2019-10-03

• Thoracic Kyphosis and Physical Function: The Framingham Study, 2017-08-21

• DNA methylation-based measures of biological age: meta-analysis predicting time to death, 2016-09-28

• Epigenome-wide Association of DNA Methylation in Whole Blood With Bone Mineral Density MORRIS ET AL, 2017-05-08

• Lower lean mass measured by dual-energy x-ray absorptiometry (DXA) is not associated with increased risk of hip fracture in women: The Framingham Osteoporosis Study, 2018-01-05

• A Meta-Analysis of the Transferability of Bone Mineral Density Genetic Loci Associations From European to African Ancestry Populations, 2020-12-18

• Putative Cut-Points in Sarcopenia Components and Incident Adverse Health Outcomes: An SDOC Analysis, 2020-07-07

• Heritability of Thoracic Spine Curvature and Genetic Correlations With Other Spine Traits: The Framingham Study, 2016-09-06

• Association of Clinical Outcomes With Surgical Repair of Hip Fracture vs Nonsurgical Management in Nursing Home Residents With Advanced Dementia, 2018-06-01

• Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes, 2021-04-23

• Bone strength estimated by micro finite element analysis (µFEA) is heritable and shares genetic predisposition with areal BMD: The Framingham Study, 2017-07-19

• Diabetes and deficits in cortical bone density, microarchitecture, and bone size: Framingham HR-pQCT Study, 2017-09-20

• Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease, 2022-09-12

• A meta-analysis of genome-wide association studies identifies multiple longevity genes, 2019-08-14

• Intermittent Nitrate Use and Risk of Hip Fracture, 2016-10-06

• Genetic basis of falling risk susceptibility in the UK Biobank Study, 2020-09-30

• Heterogeneity and Spatial Distribution of Intravertebral Trabecular Bone Mineral Density in the Lumbar Spine is Associated with Prevalent Vertebral Fracture, 2020-01-16

• Long-Term and Recent Weight Change are Associated with Reduced Peripheral Bone Density, Deficits in Bone Microarchitecture, and Decreased Bone Strength: The Framingham Osteoporosis Study, 2018-06-15

• Higher dairy food intake is associated with higher spine Quantitative Computed Tomography (QCT) bone measures in the Framingham Study for men but not women., 2018-03-30

• The Musculoskeletal Knowledge Portal: Making Omics Data Useful to the Broader Scientific Community, 2021-04-28

• Association of Abdominal Aortic Calcification with Peripheral Quantitative Computed Tomography Bone Measures in Older Women: The Perth Longitudinal Study of Ageing Women, 2022-08-13

• Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men, 2018-01-09

• Abdominal aortic calcification and risk of fracture among older women - the SOF study, 2015-06-24

• Genetics of Bone and Muscle Interactions in Humans, 2019-02-28

• Blood DNA methylation sites predict death risk in a longitudinal study of 12,300 individuals, 2020-07-22

• Dairy food intake is not associated with spinal trabecular bone score in men and women: the Framingham Osteoporosis Study, 2022-05-10

• Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at theSREBF1/TOM1L2locus, 2017-07-25

• QCT Measures of Bone Strength at the Thoracic and Lumbar Spine: The Framingham Study, 2013-07-19

• Association between dietary fiber intake and bone loss in the Framingham Offspring Study, 2017-11-07

• Identification of Novel Loci Associated With Hip Shape: A Meta-Analysis of Genomewide Association Studies, 2018-11-26

• Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass, 2017-11-07

• Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program, 2021-02-10

• Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study, 2016-12-01

• Pain Treatments after Hip Fracture among Older Nursing Home Residents, 2017-12-26

• Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study, 2018-08-29

• Correction: The complex genetics of gait speed: genome-wide meta-analysis approach, 2017-07-07

• Tai Chi for osteopenic women: design and rationale of a pragmatic randomized controlled trial, 2010-03-01

• Comparative Effectiveness of Denosumab, Teriparatide, and Zoledronic Acid among Frail Older Adults: A Retrospective Cohort Study, 2021-01-07

• Validation of the FRAiL model to predict non-vertebral and hip fractures in nursing home residents, 2019-08-28

• Analysis of the associations between the human fecal microbiome and bone density, structure and strength: the MrOS cohort, 2022-02-27

• Fisetin for COVID-19 in Skilled Nursing Facilities (COVID-FIS): Senolytic Trials in the COVID Era, 2021-08-20

• QCT Volumetric Bone Mineral Density and Vascular and Valvular Calcification: The Framingham Study, 2015-05-06

• Higher Hand Grip Strength Is Associated With Greater Radius Bone Size and Strength in Older Men and Women: The Framingham Osteoporosis Study McLean et al., 2021-03-30

• Thyroid Function and the Risk of Alzheimer's Disease: The Framingham Study, 2008-07-28

• Association of Beta Blocker Use With Bone Mineral Density in the Framingham Osteoporosis Study: A Cross-Sectional Study Lary et al., 2020-07-30