Dr. Charles Yeo, MD

• General Surgery

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• Johns Hopkins School Of Medicine

  Medical School, 1979

• Congenital Variants of Gastrointestinal Rotation Found at Resection of Hepatopancreatobiliary Tumors: A Case Series with Review of the Literature, 2016-01-01

• Celiac Axis Resection with Distal Pancreatectomy (Modified Appleby Procedure) Allows for R0 Resection of Pancreatic Body and Tail Mass Following Neoadjuvant Therapy: Case Report and Literature Review, 2016-06-01

• AraC-FdUMP[10] (CF10) is a next generation fluoropyrimidine with potent antitumor activity in PDAC and synergy withPARGinhibition, 2021-02-16

• Neoadjuvant Chemotherapy and Appleby Procedure for Pancreatic Acinar Cell Carcinoma: A Case Report, 2016-06-01

• Completion Pancreaticoduodenectomy for Hereditary Pancreatitis After Prior Puestow Procedure: A Case Report, 2018-09-25

• Advanced Endoscopic Rescue of a Complication (Duodenojejunostomy Leak) After a Pylorus-Preserving Pancreaticoduodenectomy in a Post-Esophagectomy Patient with Pancreatic Adenocarcinoma: A Case Report and Review of the Literature, 2020-02-06

• TUMOR-SPECIFIC EXPRESSION AND ALTERNATIVE SPLICING OF THE COL6A3 GENE IN PANCREATIC CANCER, 2011-06-30

• Intraductal Papillary Mucinous Neoplasm and Pancreas Divisum: Two Cases, 2016-04-01

• Nonalcoholic Fatty Liver Disease After Pancreaticoduodenectomy for a Cancer Diagnosis, 2021-03-30

• Alterations of type II classical cadherin, cadherin-10 (CDH10), is associated with pancreatic ductal adenocarcinomas, 2017-03-07

• HuR post-transcriptionally regulates WEE1: Implications for the DNA damage response in pancreatic cancer cells, 2014-02-15

• Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells, 2015-07-25

• Pylorus-Preserving Total Pancreatectomy for Intraductal Papillary Mucinous Neoplasm in the Setting of Previous Roux-en-Y Cystjejunostomy for Pancreatic Pseudocyst, 2020-01-13

• Surgeon-Led Imaging Review for Patients with Periampullary Disease: An Important Aspect of the Preoperative Consultation, 2018-09-01

• Primary Pancreatic Signet Ring Cell Carcinoma: A Case Report and Review of the Literature, 2021-01-21

• WEE1 inhibition in pancreatic cancer cells is dependent on DNA repair status in a context dependent manner, 2016-09-12

• HostIDO2gene status influences tumor progression and radiotherapy response inKRAS-driven sporadic pancreatic cancers, 2018-09-28

• Salvage endoscopic ultrasound-guided gastrojejunostomy as a bridge to definitive surgical therapy for duodenal adenocarcinoma presenting with duodenal stent obstruction, 2023-04-08

• HuR's role in gemcitabine efficacy in pancreatic cancer: HuR upregulates the expression of the gemcitabine metabolizing enzyme, deoxycytidine kinase, 2009-06-01

• Euglycemic Diabetic Ketoacidosis Due to Sodium-Glucose Cotransporter 2 Inhibitor Use in Two Patients Undergoing Pancreatectomy, 2018-11-15

• INDUCTION OF MONOCYTE CHEMOATTRACTANT PROTEIN-1 BY NICOTINE IN PANCREATIC DUCTAL ADENOCARCINOMA CELLS: ROLE OF OSTEOPONTIN, 2010-06-25

• Call for Papers: Case Reports in Pancreatic Cancer, 2016-01-01

• Effects of Hypercapnia, an Element of Obstructive Respiratory Disorders on Pancreatic Cancer Chemoresistance and Progression, 2020-02-11

• Sequencing of an Undifferentiated Carcinoma with Osteoclast-Like Giant Cells of the Pancreas: A Case Report, 2021-10-07

• "The Immune Conundrum”: Acquired Hemophilia A, Immune Thrombocytopenia, and Neutropenia in a Patient with Pancreatic Cancer, 2016-01-01

• Poly (ADP) ribose glycohydrolase can be effectively targeted in pancreatic cancer, 2019-07-04

• Induction of Osteopontin Expression by Nicotine and Cigarette Smoke in the Pancreas and Pancreatic Ductal Adenocarcinoma Cells, 2009-07-15

• Risk of Neoplastic Progression in Individuals at High Risk for Pancreatic Cancer Undergoing Long-term Surveillance, 2018-05-24

• Cytoplasmic HuR Status Predicts Disease-free Survival in Resected Pancreatic Cancer A Post-hoc Analysis From the International Phase III ESPAC-3 Clinical Trial, 2019-10-16

• A Lethally Irradiated Allogeneic Granulocyte-Macrophage Colony Stimulating Factor-Secreting Tumor Vaccine for Pancreatic Adenocarcinoma: A Phase II Trial of Safety, Efficacy, and Immune Activation, 2011-03-29

• The Pathway to Low Outlier Status in Venous Thromboembolism Events: An Analysis of Pancreatic Surgery in the National Surgical Quality Improvement Program, 2020-06-29

• A step towards personalizing next line therapy for resected pancreatic and related cancer patients: A single institution's experience, 2020-02-08

• Medical Case Reporting for Pancreatic Cancer, 2016-01-01

• Nanoparticulate delivery of diphtheria toxin DNA effectively kills Mesothelin expressing pancreatic cancer cells, 2008-10-03

• HuR Contributes to TRAIL Resistance by Restricting Death Receptor 4 Expression in Pancreatic Cancer Cells, 2016-04-06

• HuR Plays a Role in Double-Strand Break Repair in Pancreatic Cancer Cells and Regulates Functional BRCA1-Associated-Ring-Domain-1(BARD1) Isoforms, 2022-04-06

• Serum Monocyte Chemoattractant Protein-1 in Pancreatic Cancer, 2011-10-01

• Cholangio-Conundrum: A Case Series of Painless Jaundice, 2015-11-01

• Combined targeting of PARG and Wee1 causes decreased cell survival and DNA damage in an S-phase dependent manner., 2020-11-30

• Intraoperative Pancreatic Ductoscopy for Ampullary Adenocarcinoma During Pancreatic Resection: A Case Report, 2019-10-10

• Isolated Ovarian Metastasis from Pancreatic Cancer Mimicking Primary Ovarian Neoplasia: Role of Molecular Analysis in Determining Diagnosis, 2021-10-14

• HER-2-Positive Ampullary Adenocarcinoma: A Case Report, 2015-11-01

• Abemaciclib is effective against pancreatic cancer cells and synergizes with HuR and YAP1 inhibition, 2019-08-05

• Thymoquinone Promotes Pancreatic Cancer Cell Death and Reduction of Tumor Size through Combined Inhibition of Histone Deacetylation and Induction of Histone Acetylation, 2016-12-26

• A Persistent Solid Pseudopapillary Tumor of the Pancreas: Case Report and Brief Literature Review, 2015-11-01

• Minimally Invasive Distal Pancreatectomy Is Associated with Decreased Postoperative Neutrophil to Lymphocyte Ratio, 2020-05-12

• Precious Data: Interim Report from the Jefferson Pancreas Tumor Registry, 2018-06-01

• Recurrence and survival following resection of small IPMN-associated carcinomas (= 20 mm invasive component): A multi-institutional analysis, 2016-07-13

• Post-transcriptional regulation of PARG mRNA by HuR facilitates DNA repair and resistance to PARP inhibitors, 2017-07-07

• Pancreatic Mass in a Patient with a History of Resected Renal Cell Carcinoma and Resected Adenocarcinoma of the Ampulla of Vater: A Case Report, 2018-08-01

• The ‘RNA-binding ome': future implications for chemotherapeutic efficacy, 2021-09-26

• Genetic Drivers of Pancreatic Cancer Are Identical Between the Primary Tumor and a Secondary Lesion in a Long-Term (>5 Years) Survivor After a Whipple Procedure, 2018-11-01

• CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype, 2017-02-27

• Introduction toCase Reports in Pancreatic Cancer, 2015-11-01

• Phase I Evaluation of Intravenous Ascorbic Acid in Combination with Gemcitabine and Erlotinib in Patients with Metastatic Pancreatic Cancer, 2012-01-17

• pp32 (ANP32A) Expression Inhibits Pancreatic Cancer Cell Growth and Induces Gemcitabine Resistance by Disrupting HuR Binding to mRNAs, 2010-11-29

• Posttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells, 2017-06-26

• Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets, 2015-04-09

• EXPRESSION OF A PRO-METASTATIC SPLICE VARIANT OF OSTEOPONTIN, OPNC, IN HUMAN PANCREATIC DUCTAL ADENOCARCINOMA, 2009-06-29

• Hypothyroidism in Pancreatic Cancer: Role of Exogenous Thyroid Hormone in Tumor Invasion-Preliminary Observations, 2016-03-31

• Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma?, 2012-03-22

• Intraductal Papillary Mucinous Neoplasm (IPMN) with Extra-Pancreatic Mucin: A Case Series and Review of the Literature, 2012-01-19

• Genotyping and expression analysis of IDO2 in human pancreatic cancer: a novel, active target, 2011-09-12

• Chronic Obstructive Pulmonary Disease Is Associated with Worse Oncologic Outcomes in Early-Stage Resected Pancreatic and Periampullary Cancers, 2023-06-10

• Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer, 2015-04-14

• Surgical outcomes after pancreatic resection of screening-detected lesions in individuals at high-risk for developing pancreatic cancer, 2019-06-13

• Differentiating Primary Pancreatic Lymphoma Versus Primary Splenic Lymphoma: A Case Report, 2021-03-29

• Hepatoid Carcinoma of the Pancreas: A Case Report and Review of the Literature, 2015-11-01

• Cyst Fluid Biosignature to Predict Intraductal Papillary Mucinous Neoplasms of the Pancreas with High Malignant Potential, 2019-02-19

• Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer, 2013-11-04