Dr. Aysegul Sahin, MD

• Anatomic & Clinical Pathology

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• University Of Alaska / Anchorage Campus

  Medical School, 1980

• Association between germline single nucleotide polymorphisms in the PI3K-AKT-mTOR pathway, obesity, and breast cancer disease free survival, 2014-08-10

• Residual Tumor Thickness at the Tumor-Normal Tissue Interface Predicts the Recurrence-free Survival in Patients with Liver Metastasis of Breast Cancer, 2014-07-17

• Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor, 2019-03-28

• American College of Surgeons Oncology Group (ACOSOG) Z0011: Impact on Surgeon Practice Patterns, 2012-07-31

• Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity, 2016-08-30

• Clinical outcomes based on multigene profiling in metastatic breast cancer patients, 2016-10-28

• Definition of PKC-a, CDK6, and MET as therapeutic targets in triple-negative breast cancer, 2014-06-26

• Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer, 2016-11-23

• Oncogenic LncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression, 2019-06-03

• 10-year Outcomes of Breast Cancer Patients with Cytologically Confirmed Axillary Lymph Node Metastases and Pathologic Complete Response after Primary Systemic Chemotherapy, 2016-04-01

• High intra-tumoral stromal content defines Reactive breast cancer as a low-risk breast cancer subtype, 2016-05-12

• Prognostic Value of Single Nucleotide Polymorphisms of Candidate Genes Associated with Inflammation in Early Stage Breast Cancer, 2013-03-26

• The Neo-Bioscore Update for Staging Breast Cancer Treated With Neoadjuvant Chemotherapy Incorporation of Prognostic Biologic Factors Into Staging After Treatment, 2016-07-01

• Hormone Receptor Status Influences the Locoregional Benefit of Trastuzumab in Patients with Non-metastatic Breast Cancer, 2012-04-17

• Targeting Replicative Stress and DNA Repair by Combining PARP and Wee1 Kinase Inhibitors Is Synergistic in Triple Negative Breast Cancers with Cyclin E orBRCA1Alteration, 2021-04-01

• Sphingosine-kinase-1 signaling promotes metastasis of triple-negative breast cancer, 2019-06-25

• A Molecular Portrait of High-Grade Ductal CarcinomaIn Situ, 2015-08-06

• CD8+T cells inhibit metastasis and CXCL4 regulates its function, 2021-04-01

• Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer, 2019-03-13

• Outcomes of Sentinel Lymph Node Dissection Alone vs. Axillary Lymph Node Dissection in Early Stage Invasive Lobular Carcinoma: A Retrospective Study of the Surveillance, Epidemiology and End Results (SEER) Database, 2014-02-25

• Multidisciplinary Considerations in the Implementation of the Findings from the American College of Surgeons Oncology Group (ACOSOG) Z0011 Study: A Practice-Changing Trial, 2015-02-06

• Effectiveness and Safety of Magseed-localization for Excision of Breast Lesions: A Prospective, Phase IV Trial, 2020-07-31

• Prognostic Impact of High Baseline Stromal Tumor-Infiltrating Lymphocytes in the Absence of Pathologic Complete Response in Early-Stage Triple-Negative Breast Cancer, 2022-03-04

• Eradication of triple negative breast cancer cells by targeting glycosylated PD-L1, 2018-02-12

• 14-3-3? turns TGF-ß's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2, 2015-02-09

• Correlation between CpG methylation profiles and hormone receptor status in breast cancers, 2007-08-31

• Expanding Implementation of ACOSOG Z0011 in Surgeon Practice, 2017-10-13

• Expression of PD-1 and PD-L1 in Extramammary Paget Disease: Implications for Immune-Targeted Therapy, 2019-05-29

• Mutations in Homologous Recombination Genes and Loss of Heterozygosity Status in Advanced-Stage Breast Carcinoma†, 2023-04-28

• Deubiquitination and Stabilization of PD-L1 by CSN5, 2016-11-17

• Evaluation of Prognosis in Hormone Receptor-Positive/HER2-Negative and Lymph Node-Negative Breast Cancer With Low Oncotype DX Recurrence Score, 2017-12-14

• Cancer stem cell markers are enriched in normal tissue adjacent to triple negative breast cancer and inversely correlated with DNA repair deficiency, 2013-09-04

• Rate of reclassification of HER2-equivocal breast cancer cases to HER2-negative per the 2018 ASCO/CAP guidelines and response of HER2-equivocal cases to anti-HER2 therapy, 2020-11-12