Dr. Andrew Brohl, MD

• Medical Oncology

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• Combined BRAF and HSP90 inhibition in patients with unresectableBRAFV600E mutant melanoma, 2018-04-19

• Mutant p53s and chromosome 19 microRNA cluster overexpression regulate cancer testis antigen expression and cellular transformation in hepatocellular carcinoma, 2021-06-16

• Response to sunitinib of a gastrointestinal stromal tumor with a rare exon 12PDGFRAmutation, 2015-09-21

• The genomic landscape of malignant peripheral nerve sheath tumors: diverse drivers of Ras pathway activation, 2017-11-08

• A phase IB study of ipilimumab with peginterferon alfa-2b in patients with unresectable melanoma, 2016-12-20

• Early objective response to avelumab treatment is associated with improved overall survival in patients with metastatic Merkel cell carcinoma, 2019-02-05

• A Case of Retroperitoneal Synovial Sarcoma in Pregnancy Treated with Antepartum Doxorubicin plus Ifosfamide Chemotherapy, 2021-07-16

• The genomic landscape of undifferentiated embryonal sarcoma of the liver is typified by C19MC structural rearrangement and overexpression combined withTP53mutation or loss, 2020-04-20

• Anti-PD-1 therapy in advanced sarcomas: is cutaneous primary site a stronger predictor of response than histologic subtype?, 2023-03-13

• Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell lines, 2019-09-24

• An analysis of the use of targeted therapies in patients with advanced Merkel cell carcinoma and an evaluation of genomic correlates of response, 2021-07-16

• Classical epithelial-mesenchymal transition (EMT) and alternative cell death process-driven blebbishield metastatic-witch (BMW) pathways to cancer metastasis, 2022-08-23

• Regulation ofMYO18BmRNA by a network of C19MC miRNA-520G, IFN-?, CEBPB, p53 and bFGF in hepatocellular carcinoma, 2020-07-23

• PIK3CA-Related Overgrowth Syndrome (PROS) and Angiosarcoma: A Case Report, 2020-04-17

• Chromosome 19 miRNA cluster and CEBPB expression specifically mark and potentially drive triple negative breast cancers, 2018-10-18

• Evaluation of Targeted Next-Generation Sequencing for the Management of Patients Diagnosed with a Cancer of Unknown Primary, 2022-01-28

• Frequent inactivating germline mutations in DNA repair genes in patients with Ewing sarcoma Germline mutations in Ewing sarcoma, 2017-01-26

• Cetuximab for Immunotherapy-Refractory/Ineligible Cutaneous Squamous Cell Carcinoma, 2023-06-14

• A Randomized Phase II Trial of Combined Nivolumab and Ipilimumab with or without Stereotactic Body Radiation Therapy for Advanced Merkel Cell Carcinoma, 2022-09-12

• Delivery of Online Adaptive MRI-Guided Radiation Therapy for a Deaf Patient, 2022-08-01

• Development and clinical application of an integrative genomic approach to personalized cancer therapy, 2016-06-01

• A Malignant Glomus Tumor of the Liver Harboring MIR143-NOTCH2 Rearrangement: From Diagnosis to Management, 2022-10-26

• Neoadjuvant BRAF-targeted therapy in regionally advanced and oligometastatic melanoma, 2019-09-12

• Combination of Ipilimumab and Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes for Patients with Metastatic Melanoma, 2018-03-02

• Identification of a novelMTAP-RAF1fusion in a soft tissue sarcoma, 2018-10-12

• The Genomic Landscape of Merkel Cell Carcinoma and Clinicogenomic Biomarkers of Response to Immune Checkpoint Inhibitor Therapy, 2019-08-09

• Multi-Dimensional Omics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: Report from Pediatric Oncology Branch, NCI, 2016-03-18

• Increased incidence ofFBXW7andPOLEproofreading domain mutations in young adult colorectal cancers, 2016-05-31

• Chemotherapy improves distant control in localized high-grade soft tissue sarcoma of the extremity/trunk, 2020-07-09

• Immuno-transcriptomic profiling of extracranial pediatric solid malignancies, 2021-11-23