Dr. Amr Sawalha, MD

• Rheumatology

*Healthgrades does not verify qualifications for medical specialties. Please verify your provider's specialty and qualifications directly with your provider and applicable medical board.

• Jordan University Of Science And Technology

  Medical School, 1998

• The lupus susceptibility alleleDRB1*03:01encodes a disease-driving epitope, 2022-07-28

• Monogenic Lupus: A Developing Paradigm of Disease, 2018-10-30

• Inhibition of EZH2 ameliorates lupus-like disease in MRL/lprmice, 2019-08-12

• Epigenome-wide scan identifies a treatment-responsive pattern of altered DNA methylation among cytoskeletal remodeling genes in monocytes and CD4+ T cells in Behcet's disease, 2014-04-15

• Epigenetic Variability in Systemic Lupus Erythematosus: What We Learned from Genome-Wide DNA Methylation Studies, 2018-02-13

• Drug-induced lupus erythematosus: an update on drugs and mechanisms, 2020-06-02

• EZH2 modulates the DNA methylome and controls T cell adhesion through junctional adhesion molecule-A in lupus patients, 2017-12-15

• Trans-Ancestral Studies Fine Map the SLE-Susceptibility LocusTNFSF4, 2013-07-18

• Histone Deacetylase 5 is Overexpressed in Scleroderma Endothelial Cells and Impairs Angiogenesis via Repressing Pro-angiogenic Factors, 2016-08-11

• Activation of the JAK/STAT pathway in Behcet's Disease, 2014-11-20

• HLA-DRB1allelic epitopes that associate with autoimmune disease risk or protection activate reciprocal macrophage polarization, 2021-01-28

• The genetics of Takayasu arteritis, 2017-07-26

• Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies, 2014-05-08

• Unfolding the Pathogenesis of Scleroderma through Genomics and Epigenomics, 2017-05-16

• T CELL PKCd KINASE INACTIVATION INDUCES LUPUS-LIKE AUTOIMMUNITY IN MICE, 2015-03-28

• Genome-wide DNA methylation patterns in naive CD4+T cells from patients with primary Sjogren's syndrome, 2013-12-26

• Centromere defects, chromosome instability, and cGAS-STING activation in systemic sclerosis, 2022-11-18

• Methyl-CpG-binding protein 2 mediates antifibrotic effects in scleroderma fibroblasts, 2018-05-14

• Structural variation of centromeric endogenous retroviruses in human populations and their impact on cutaneous T-cell lymphoma, Sezary syndrome, and HIV infection, 2019-05-02

• IFI44Lpromoter methylation as a blood biomarker for systemic lupus erythematosus, 2016-01-19

• Autoimmune disease in the epigenetic era: how has epigenetics changed our understanding of disease and how can we expect the field to evolve?, 2015-11-03

• Takayasu arteritis risk locus inIL6represses the anti-inflammatory geneGPNMBthrough chromatin looping and recruiting MEF2-HDAC complex, 2019-07-17

• Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Subchondral Bone and Similarity to Overlying Cartilage, 2017-04-12

• Sex chromosome contributions to sex differences in multiple sclerosis susceptibility and progression, 2018-02-13

• Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils, 2015-01-28

• Genome-wide DNA methylation analysis in primary antiphospholipid syndrome neutrophils, 2018-11-22

• Overexpression of methyl-CpG-binding protein 2 and autoimmunity: Evidence fromMECP2duplication syndrome, lupus,MECP2transgenic andMecp2deficient mice, 2013-07-16

• Epigenetic reprogramming in naive CD4+ T cells favoring T cell activation and non-Th1 effector T cell immune response as an early event in lupus flares, 2016-04-23

• Genome-wide association study identifies susceptibility loci inIL6,RPS9/LILRB3, and an intergenic locus on chromosome 21q22 in Takayasu's arteritis, 2015-03-04

• Novel transcriptional activity and extensive allelic imbalance in the human MHC region, 2018-01-08

• Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naive CD4+ T cells from lupus patients, 2013-04-24

• Ethnicity-specific epigenetic variation in naive CD4+ T cells and the susceptibility to autoimmunity, 2015-11-24

• The DNA methylation signature of human TCRaß+CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune response, 2014-10-29

• Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy, 2017-03-09

• Functional characterization of theMECP2/IRAK1lupus risk haplotype in human T cells and a humanMECP2transgenic mouse, 2013-02-18

• CD4+CD28+KIR+CD11ahiT cells correlate with disease activity and are characterized by a pro-inflammatory epigenetic and transcriptional profile in lupus patients, 2017-10-20

• Hypomethylation ofSTAT1andHLA-DRB1is associated with type-I interferon-dependentHLA-DRB1expression in lupus CD8+ T cells, 2019-01-23

• An update on the role of epigenetics in systemic vasculitis, 2018-02-03

• Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis, 2018-01-27

• Identifying CYR61 as a Potential Anti-fibrotic and Pro-angiogenic Mediator in Scleroderma, 2019-06-12

• GFP Affects Human T Cell Activation and Cytokine Production followingIn VitroStimulation, 2013-04-05

• Diet Influences Expression of Autoimmune Associated Genes and Disease Severity By Epigenetic Mechanisms in a Transgenic Lupus Model, 2013-06-19

• Renal involvement in lupus is characterized by unique DNA methylation changes in naive CD4+ T cells, 2015-05-23

• Deoxyribonucleic Acid Methylation in Systemic Lupus Erythematosus: Implications for Future Clinical Practice, 2018-04-24