Dr. Alexander Pearson, MD

• Medical Oncology

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• University Of Rochester

  Medical School

• Machine Learning-Guided Adjuvant Treatment of Head and Neck Cancer Machine Learning-Guided Adjuvant Treatment of Head and Neck Cancer, 2020-11-19

• A validated mathematical model of FGFR3-mediated tumor growth reveals pathways to harness the benefits of combination targeted therapy and immunotherapy in bladder cancer, 2021-05-19

• Data augmentation and multimodal learning for predicting drug response in patient-derived xenografts from gene expressions and histology images, 2023-03-07

• The emerging role of immune checkpoint inhibitors for the treatment of breast cancer, 2021-10-11

• Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration, 2018-12-26

• Development and Validation of a Decision Analytical Model for Posttreatment Surveillance for Patients With Oropharyngeal Carcinoma Decision Analytical Model for Posttreatment Surveillance for Patients With Oropharyngeal Carcinoma, 2022-04-13

• Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer, 2019-06-03

• Deep learning in cancer pathology: a new generation of clinical biomarkers, 2020-11-18

• UM-HACC-2A: MYB-NFIB fusion-positive human adenoid cystic carcinoma cell line, 2018-10-18

• In silico models accurately predict in vivo response for IL-6 blockade in head and neck cancer, 2020-02-10

• A robust and interpretable gene signature for predicting the lymph node status of primary T1/T2 oral cavity squamous cell carcinoma, 2021-10-14

• Uncertainty-informed deep learning models enable high-confidence predictions for digital histopathology, 2022-11-02

• Comparing scientific abstracts generated by ChatGPT to real abstracts with detectors and blinded human reviewers, 2023-04-26

• AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling, 2022-08-05

• Deep learning-based subtyping of gastric cancer histology predicts clinical outcome: a multi-institutional retrospective study, 2023-06-03

• Sampling from single-cell observations to predict tumor cell growthin-vitroandin-vivo, 2017-11-25

• Clinical-grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning, 2020-06-17

• Characterizing Lymph Node Burden With Elective Unilateral Neck Irradiation in Human Papillomavirus-Positive Tonsil Squamous Cell Carcinoma: Defining the Upper Limits, 2022-07-31

• Deep learning prediction of BRAF-RAS gene expression signature identifies noninvasive follicular thyroid neoplasms with papillary-like nuclear features, 2020-12-10

• The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View, 2020-02-07

• Artificial Intelligence Can Cut Costs While Maintaining Accuracy in Colorectal Cancer Genotyping, 2021-06-08

• Ablation of cancer stem cells by therapeutic inhibition of the MDM2-p53 interaction in mucoepidermoid carcinoma, 2018-11-29

• Deep learning prediction of BRAF-RAS gene expression signature identifies noninvasive follicular thyroid neoplasms with papillary-like nuclear features, 2020-12-10

• A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer, 2022-08-17

• Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer: a retrospective multicentre cohort study, 2021-08-17

• Wnt-ß-catenin activation epigenetically reprograms Tregcells in inflammatory bowel disease and dysplastic progression, 2021-03-04

• Machine learning can identify newly diagnosed patients with CLL at high risk of infection, 2020-01-17

• Self-supervised attention-based deep learning for pan-cancer mutation prediction from histopathology, 2023-03-28

• COVIDomic: A multi-modal cloud-based platform for identification of risk factors associated with COVID-19 severity, 2021-07-14

• Human Endogenous Retrovirus Expression Is Associated with Head and Neck Cancer and Differential Survival, 2020-08-28

• Highly accurate response prediction in high-risk early breast cancer patients using a biophysical simulation platform, 2022-09-05

• The impact of site-specific digital histology signatures on deep learning model accuracy and bias, 2021-07-20

• Author Correction: A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer, 2022-12-21

• Integration of clinical features and deep learning on pathology for the prediction of breast cancer recurrence assays and risk of recurrence, 2023-04-14

• Doublecortin-Like Kinase 1 (DCLK1) Is a Novel NOTCH Pathway Signaling Regulator in Head and Neck Squamous Cell Carcinoma, 2021-07-16