Dr. Adel El-Naggar, MD

• Anatomic & Clinical Pathology

*Healthgrades does not verify qualifications for medical specialties. Please verify your provider's specialty and qualifications directly with your provider and applicable medical board.

• University Of Tex Md Anderson Cancer Center

  Fellowship Hospital, 1987

• University Hospitals Of Cleveland

  Residency Hospital, 1986

• Ein-shams University Hosps

  Residency Hospital, 1974

• Ein-shams University Hosps

  Internship Hospital, 1971

• University Ein Shams, Cairo

  Medical School, 1970

• A Phase II study of Gefitinib in Patients with Advanced Salivary Gland Cancers, 2015-03-30

• Association between a Functional Polymorphism (-1195T>C) in theIGFBP5Promoter and Head and Neck Cancer Risk, 2010-10-14

• The role of elective-nodal irradiation for esthesioneuroblastoma patients with clinically negative neck, 2015-11-10

• High Rate of BRAF and RET/PTC Dual Mutations Associated with Recurrent Papillary Thyroid Carcinoma, 2009-01-15

• Integrative genomic characterization of oral squamous cell carcinomaidentifies frequent somatic drivers, 2013-04-25

• Enhanced MDM2 Oncoprotein Expression in Soft Tissue Sarcoma: Several Possible Regulatory Mechanisms, 1997-03-01

• Mutational landscape of aggressive cutaneous squamous cell carcinoma, 2014-10-10

• Molecular imaging of glucose uptake in oral neoplasia following topical application of fluorescently labeled deoxy-glucose, 2009-06-01

• Spatial PD-L1, immune-cell microenvironment and genomic copy-number alteration patterns and drivers of invasive-disease transition in prospective oral precancer cohort, 2023-01-03

• Mitochondrial Mutations in Adenoid Cystic Carcinoma of the Salivary Glands, 2009-12-30

• A Comparison of the Demographics, Clinical Features, and Survival of Patients with Adenoid Cystic Carcinoma of Major and Minor Salivary Glands Versus Less Common Sites within the SEER Registry, 2011-12-16

• New DNA methylation markers and global DNA hypomethylation are associated with oral cancer development, 2015-09-04

• A Novel Target for Oral Cancer Chemoprevention? Notch Quite, Yet…, 2015-02-24

• Elective Neck Dissection Versus Observation in Patients With Head and Neck Cutaneous Squamous Cell Carcinoma, 2021-08-06

• Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets, 2020-11-10

• Squamous cell carcinoma of the oral tongue in young non-smokers is genomically similar to tumors in older smokers, 2014-05-29

• Primary Colonic -Type Adenocarcinoma of the Base of the Tongue: a Previously Unreported Phenotype, 2009-08-19

• Alterations Associated with Androgen Receptor Gene Activation in Salivary Duct Carcinoma (SDC) of Both Sexes: Potential Therapeutic Ramifications, 2014-10-14

• DEAR1 Is a Dominant Regulator of Acinar Morphogenesis and an Independent Predictor of Local Recurrence-Free Survival in Early-Onset Breast Cancer, 2009-05-05

• A common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization (WHO) expert consensus proposal, 2018-08-23

• Developmental transcription factor EN1- novel biomarker in human salivary gland adenoid cystic carcinoma, 2011-07-28

• Whole-Genome Sequencing of Common Salivary Gland Carcinomas: Subtype-Restricted and Shared Genetic Alterations, 2021-05-19

• Prediction of Neck Dissection Requirement After Definitive Radiotherapy for Head and Neck Squamous Cell Carcinoma, 2012-03-01

• Role of COX-2 in tumor progression and survival of head and neck squamous cell carcinoma, 2009-09-08

• Noninvasive Evaluation of Oral Lesions Using Depth-Sensitive Optical Spectroscopy, 2009-04-15

• Compliance with Quality Assurance Measures in Patients Treated for Early Oral Tongue Cancer, 2010-07-15

• Phase II Randomized, Placebo-controlled Trial of Green Tea Extract in Patients with High-risk Oral Premalignant Lesions, 2014-11-15

• Reduced DNA Repair Capacity for Removing Tobacco Carcinogen-Induced DNA Adducts Contributes to Risk of Head and Neck Cancer but not Tumor Characteristics, 2010-01-12

• Phase II Trial of Induction Chemotherapy Followed by Surgery for Squamous Cell Carcinoma of the Oral Tongue in Young Adults, 2011-10-19

• Long-Term Update of NRG/RTOG 0522: A Randomized Phase 3 Trial of Concurrent Radiation and Cisplatin With or Without Cetuximab in Locoregionally Advanced Head and Neck Cancer, 2022-12-19

• Highly prevalentTERTpromoter mutations in aggressive thyroid cancers, 2013-07-12

• Sinonasal neuroendocrine carcinoma: impact of differentiation status on response and outcome, 2011-07-27

• PD-1 blockade prevents the development and progression of carcinogen-induced oral premalignant lesions, 2017-10-10

• The future of medical diagnostics: review paper, 2011-08-23

• Epigenetic screening of salivary gland mucoepidermoid carcinoma identifies hypomethylation of CLIC3 as a common alteration, 2015-10-17

• Early postoperative epidermal growth factor receptor inhibition is safe and effective in inhibiting microscopic residual of oral squamous cell carcinomain vivo, 2012-02-24

• Differential gene expression profiling of aggressive and non-aggressive follicular carcinomas, 2011-03-21

• Genetic Variants in Selected pre-mircroRNA Genes and Risk of Squamous Cell Carcinoma of the Head and Neck, 2010-10-15

• A Phase II Study of Gefitinib for Aggressive Cutaneous Squamous Cell Carcinoma of the Head and Neck, 2012-01-18

• Reciprocal and Autonomous Glucocorticoid and Androgen Receptor Activation in Salivary Duct Carcinoma, 2019-11-26

• LMW cyclin E and its novel catalytic partner CDK5 are therapeutic targets and prognostic biomarkers in salivary gland cancers, 2021-05-14

• An Orthotopic Murine Model of Sinonasal Malignancy, 2008-11-15

• At the frontiers of surgery: review, 2011-02-09

• Akt/mammalian target of rapamycin counteract the antitumor activities of cixutumumab an anti-insulin-like growth factor I receptor monoclonal antibody, 2011-10-06

• PI3-kinase Pathway Biomarkers in Oral Cancer and Tumor Immune Cells, 2018-12-16

• Chromosomal abnormalities and molecular landscape of metastasizing mucinous salivary adenocarcinoma, 2017-01-09

• Genetic and Expression Analysis of HER-2 and EGFR Genes in Salivary Duct Carcinoma: Empirical and Therapeutic Significance, 2010-04-06

• Epithelial Mutant p53 Promotes Resistance to Anti-PD-1-Mediated Oral Cancer Immunoprevention in Carcinogen-Induced Mouse Models, 2021-03-23

• Oncogenic Orphan Nuclear Receptor NR4A3 Interacts and Cooperates with MYB in Acinic Cell Carcinoma, 2020-08-27

• Comprehensive Analysis of theMYB-NFIBGene Fusion in Salivary Adenoid Cystic Carcinoma: Incidence, Variability and Clinicopathological Significance, 2010-08-11

• MicroRNA Profiling of Salivary Adenoid Cystic Carcinoma: Association of miR-17-92 Upregulation with Poor Outcome, 2013-06-25

• NovelMYBL1gene rearrangements with recurrentMYBL1-NFIBfusions in salivary adenoid cystic carcinomas lacking t(6;9) translocations, 2015-12-02

• An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma, 2016-02-01

• Dicer1 phospho-mimetic promotes tumor progression and dissemination, 2019-03-26

• Transcriptomes define distinct subgroups of salivary gland adenoid cystic carcinoma with different driver mutations and outcomes, 2017-12-23

• Rearrangements, Expression, and Clinical Significance of MYB and MYBL1 in Adenoid Cystic Carcinoma: A Multi-Institutional Study, 2022-07-28

• Dominant Gene Expression Profiles Define Adenoid Cystic Carcinoma (ACC) from Different Tissues: Validation of a Gene Signature Classifier for Poor Survival in Salivary Gland ACC, 2023-02-22

• Proton Beam Therapy for Head and Neck Carcinoma of Unknown Primary: Toxicity and Quality of Life, 2021-06-25

• N-Terminal Truncated Myb with New Transcriptional Activity Produced Through Use of an Alternative MYB Promoter in Salivary Gland Adenoid Cystic Carcinoma, 2019-12-21

• Proton Therapy for Head and Neck Cancer: A 12-Year, Single-Institution Experience, 2021-06-25

• Genome-Wide Association Study Identifies Common Genetic Variants Associated with Salivary Gland Carcinoma and its Subtypes, 2015-03-30

• Differential gain-of-function activity of three p53 hotspot mutantsin vivo, 2022-05-16

• KRAS-variant is a biomarker of cetuximab response potentially through altered immunity in head and neck cancer: Re-analysis of NRG Oncology/RTOG 0522 Subtitle: TheKRAS-variant and cetuximab response in HNSCC, 2017-04-01

• Long-Term Outcomes Following Multi-Disciplinary Management of T3 Larynx Squamous Cell Carcinomas: Modern Therapeutic Approaches Improve Functional Outcomes and Survival, 2016-07-28

• Rheumatoid arthritis mimicking metastatic squamous cell carcinoma, 2011-05-14

• DNA FISH Diagnostic Assay on Cytological Samples of Thyroid Follicular Neoplasms†, 2020-09-06

• Pilot phase II trial of Neoadjuvant Immunotherapy in Locoregionally Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck, 2021-06-29

• Cdkn2asuppresses metastasis in squamous cell carcinomas induced by the gain-of-function mutantp53R172H, 2021-10-31

• Family History of Cancer and Risk of Sporadic Differentiated Thyroid Carcinoma, 2011-07-28

• p53mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer, 2012-06-12

• Prognostic biomarkers in patients with human immunodeficiency virus-positive disease with head and neck squamous cell carcinoma, 2017-09-25

• Gain-of-function mutant p53 but not p53 deletion promotes head and neck cancer progression in response to oncogenic K-ras, 2011-09-26

• Molecular Profiling of Sinonasal Undifferentiated Carcinoma, 2013-04-30

• EXPRESSION AND SIGNIFICANCE OF NOTCH SIGNALING PATHWAY IN SALIVARY ADENOID CYSTIC CARCINOMA, 2013-10-10

• Novel Chromosomal Rearrangements and breakpoints at the t(6;9) in Salivary Adenoid Cystic Carcinoma: association withMYB-NFIBchimeric fusion,MYBexpression, and clinical outcome, 2011-10-05

• Final Report of a Prospective Randomized Trial to Evaluate the Dose-Response Relationship for Postoperative Radiation Therapy and Pathologic Risk Groups in Patients with Head and Neck Cancer, 2017-07-10

• SomaticTrp53mutations differentially drive breast cancer and evolution of metastases, 2018-09-27

• Prognostic Factors Associated With Decreased Survival in Patients With Acinic Cell Carcinoma, 2017-07-10

• Functional Variants of theNEIL1andNEIL2Genes and Risk and Progression of Squamous Cell Carcinoma of the Oral Cavity and Oropharynx, 2008-07-01

• Squamous cell carcinoma of the oral cavity often overexpresses p16 but is rarely driven by human papillomavirus, 2016-03-21

• Serum signature of hypoxia-regulated factors is associated with progression after induction therapy in head and neck squamous cell cancer, 2010-06-08

• Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma, 2021-01-07

• CD147 and Ki-67 overexpression confers poor prognosis in squamous cell carcinoma of oral tongue: A tissue microarray study, 2015-01-07

• Objective Detection and Delineation of Oral Neoplasia Using Autofluorescence Imaging, 2009-04-28

• ActivatingNOTCH1mutations define a distinct subgroup of adenoid cystic carcinoma patients with poor prognosis, propensity to bone and liver metastasis, and potential responsiveness to Notch1 inhibitors, 2016-11-21

• Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations inNOTCH1, 2011-07-28